331-01-011 / 331-01-011 ISMRM Abstract

Direction-Specific DTI Changes in Motor Cortex After Sparse Ablation of Intratelencephalic Pyramidal Neurons

Primary: Diffusion - Microstructure

Secondary: Preclinical Animal & in vitro MR - Biology, Models, Methods

331-01-011 · Neuro Imaging and Metabolism · Monday, 11 May, 8:20 AM–10:10 AM · Roof Terrace

Keywords: Biomarkers Ablation Animal mouse model Diffusion Tensor Imaging (DTI)

Accepted

Emma L Thomson ¹, Mihai Atudorei¹, Hartwig R Siebner^1,2,3, Mattias Rickhag^1,2, Tim B Dyrby^1,4

¹Department of Radiology and Nuclear Medicine - Amager and Hvidovre, Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Copenhagen, Denmark

²University of Copenhagen, Copenhagen, Denmark

³Copenhagen University Hospital - Bispebjerg, Copenhagen, Denmark

⁴Department of Applied Mathematics and Computer Science, Technical University of Denmark, Kgs. Lyngby, Denmark

Presenting Author: Emma L Thomson

Synopsis

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References

1. Atudorei et al. 2025. Neurobiology of Disease. 204;106755. https://doi.org/10.1016/j.nbd.2024.106755. [doi]

2. Beachum et al. Preprint. bioRXiv. https://doi.org/10.1101/2024.09.06.611719 [doi]

3. Kjer et al. 2025. eLife. 13:RP94917. https://doi.org/10.7554/eLife.94917.3. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/331-01-011