Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
531-01-004 / 531-01-004 ISMRM Abstract

Predicting Full-Dose Gadolinium T1 and T2 Maps from Low-Dose Multiparametric Acquisitions

Accepted
Unay Dorken Gallastegi1,2, Yohan Jun1,2, Yuting Chen1,2,3, Xingwang Yong1,2, Camilo Calixto1,4, Sergio Valencia1,4, Shohei Fujita1,2, Patricia E Grant1,5, Seonghwan Yee1,2, Jason Stockmann1,2, Borjan Gagoski1,5, Camilo Jaimes1,4, Berkin Bilgic1,2,6
1Harvard Medical School, Boston, United States of America
2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America
3State Key Laboratory of Extreme Photonics and Instrumentation,, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China
4Massachusetts General Hospital, Boston, United States of America
5Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children’s Hospital, Boston, United States of America
6Harvard-MIT Health Sciences and Technology, Cambridge, United States of America
Presenting Author: Yiyun Dong

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Carr DH, Brown J, Bydder GM, Steiner RE, Weinmann HJ, Speck U, et al. Gadolinium-DTPA as a contrast agent in MRI: initial clinical experience in 20 patients. AJR Am J Roentgenol. 1984;143(2):215-24. doi:10.2214/ajr.143.2.215. PMID:6611046. [doi] [pmid]
2. Iyad N, Ahmad MS, Alkhatib SG, Hjouj M. Gadolinium contrast agents: challenges and opportunities of a multidisciplinary approach. Eur J Radiol Open. 2023;11:100503. doi:10.1016/j.ejro.2023.100503. PMID:37456927 [doi] [pmid]
3. Zahra MA, Hollingsworth KG, Sala E, Lomas DJ, Tan LT. Dynamic contrast-enhanced MRI as a predictor of tumour response to radiotherapy. Lancet Oncol. 2007;8(1):63-74. doi:10.1016/S1470-2045(06)71012-9. PMID:17196512. [doi] [pmid]
4. Zech CJ, Herrmann KA, Reiser MF, Schoenberg SO. MR imaging in patients with suspected liver metastases: value of liver-specific contrast agent Gd-EOB-DTPA. Magn Reson Med Sci. 2007;6(1):43-52. doi:10.2463/mrms.6.43. PMID:17510541. [doi] [pmid]
5. Luo Y, Gao C, Chen W, Zhou K, Xu M. Molecular magnetic resonance imaging with contrast agents for assessment of inflammatory bowel disease: a systematic review. Contrast Media Mol Imaging. 2020;2020:4764985. doi:10.1155/2020/4764985. [doi]
6. Rogosnitzky M, Branch S. Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms. Biometals. 2016;29(3):365-76. doi:10.1007/s10534-016-9931-7. PMID:27053146; PMCID:PMC4879157. [doi] [pmid]
7. Ramalho J, Semelka RC, Ramalho M, Nunes RH, AlObaidy M, Castillo M. Gadolinium-based contrast agent accumulation and toxicity: an update. AJNR Am J Neuroradiol. 2016;37(7):1192-8. doi:10.3174/ajnr.A4615. PMID:26659341; PMCID:PMC7960350. [doi] [pmid]
8. Kvernby S, Warntjes MJA, Haraldsson H, Carlhäll CJ, Engvall J, Ebbers E. Simultaneous three-dimensional myocardial T1 and T2 mapping in one breath hold with 3D-QALAS. J Cardiovasc Magn Reson. 2014;16:102. doi:10.1186/s12968-014-0102-8. PMID:25287941; PMCID:PMC4169802. [doi] [pmid]
9. Jun Y, Cho J, Wang X, Gee M, Grant PE, Bilgic B, Gagoski B. SSL-QALAS: Self-supervised learning for rapid multiparameter estimation in quantitative MRI using 3D-QALAS. Magn Reson Med. 2023;90(5):2019-2032. doi:10.1002/mrm.29786. PMID:37415389; PMCID:PMC10527557. [doi] [pmid]
10. Elster AD. How much contrast is enough? Dependence of enhancement on field strength and MR pulse sequence. Eur Radiol. 1997;7(Suppl 5):S276-80. doi:10.1007/s003300050379. PMID:9308654. [doi] [pmid]
11. Gong E, Pauly JM, Wintermark M, Zaharchuk G. Deep learning enables reduced gadolinium dose for contrast-enhanced brain MRI. J Magn Reson Imaging. 2018;48(2):330-40. doi:10.1002/jmri.25970. PMID:29437269. [doi] [pmid]
12. Hernando D, Kellman P, Haldar J, Liang ZP. Estimation of water/fat images, B0 field map and T2* map using VARPRO. In: Proceedings of the 16th Annual Meeting of ISMRM, Toronto, Canada 2008 May 3 (Vol. 1517).
13. Barral JK, Gudmundson E, Stikov N, Etezadi-Amoli M, Stoica P, Nishimura DG. A robust methodology for in vivo T1 mapping. Magn Reson Med. 2010;64(4):1057-67. doi:10.1002/mrm.22497. PMID:20564597; PMCID:PMC2962940. [doi] [pmid]
14. Chan SH, Wang X, Elgendy OA. Plug-and-Play ADMM for image restoration: fixed-point convergence and applications. IEEE Trans Comput Imaging. 2017;3(1):84-98. doi:10.1109/TCI.2016.2629286. [doi]

Cite this abstract