Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
363-03-009 MRI in Clinical Practice Abstract

MRI in Clinical Practice: In vivo Multiparametric Mapping of Microstructural Changes in Parkinson’s Disease

Primary: Neuro - Parkinson's Disease
Secondary: Neuro - Other Neurodegeneration
363-03-009 · MRI in Clinical Practice: Diagnostic Applications, Quantitative Imaging, and Emerging Techniques · Monday, 11 May, 1:50 PM–2:45 PM · Digital Posters Row D
Keywords: Neurodegeneration Parkinson's Disease Quantitative MRI Multiparametric mapping
Accepted
Marta M Pokotylo 1,2, Martin Göttlich3, Laura Schmidt1,4, Helena S Weingarten1,4, Lydia Dirksen1,4, Lea Albrecht1,4, Norman Griebner1,2, Jan Uter1,4, Julia Henkel1,4, Norbert Brüggemann1,4, Jannik Prasuhn1,4,5,6
1Section of Movement Disorders, Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany
2Department of Neurology, University of Luebeck, Luebeck, Germany
3Institute of Medical Psychology, University of Luebeck, Luebeck, Germany
4Institute of Neurogenetics, University of Luebeck, Luebeck, Germany
5Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, United States of America
6F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, United States of America
Presenting Author: Marta M Pokotylo

Synopsis

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References

1. 1. Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez‐Martin P, et al. Movement Disorder Society‐sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results. Mov Disord. 2008 Nov 15;23(15):2129–70. doi: 10.1002/mds.22340 [doi]
2. 2. Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, et al. The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. J Am Geriatr Soc. 2005 Apr;53(4):695–9. doi: 10.1111/j.1532-5415.2005.53221.x [doi]
3. 3. Weiskopf N, Suckling J, Williams G, Correia MM, Inkster B, Tait R, et al. Quantitative multi-parameter mapping of R1, PD*, MT, and R2* at 3T: a multi-center validation. Front Neurosci. 2013;7. doi: 10.3389/fnins.2013.00095 [doi]
4. 4. Tabelow K, Balteau E, Ashburner J, Callaghan MF, Draganski B, Helms G, et al. hMRI – A toolbox for quantitative MRI in neuroscience and clinical research. NeuroImage. 2019 July;194:191–210. doi: 10.1016/j.neuroimage.2019.01.029 [doi]
5. 5. Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, et al. MDS clinical diagnostic criteria for Parkinson’s disease: MDS-PD Clinical Diagnostic Criteria. Mov Disord. 2015 Oct;30(12):1591–601. doi: 10.1002/mds.26424 [doi]
6. 6. Mezer A, Rokem A, Berman S, Hastie T, Wandell BA. Evaluating quantitative proton‐density‐mapping methods. Hum Brain Mapp. 2016 Oct;37(10):3623–35. doi: 10.1002/hbm.23264 [doi]
7. 7. Trang H, Hartung TJ, Chen Q, Hetzer S, Chien C, Sperber PS, et al. A quantitative multi-parameter mapping protocol standardized for clinical research in multiple sclerosis. Sci Rep. 2024 Dec;14(1). doi: 10.1038/s41598-024-80274-9 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/363-03-009