Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
669-02-012 ISMRM Abstract

Fixel-Based Analysis Reveals Key Pathway of White Matter Injury in Pediatric Spastic Cerebral Palsy

Primary: Neuro - White Matter
Secondary: Pediatrics - Neuro
669-02-012 · Neuroimaging Biomarkers Across the Spectrum of Brain Disorders · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row J
Accepted
Yitong Bian 1, Xiao Yan1, Zhen Jia1, Zhe Liu1, Xianjun Li1, jian Yang1
1Department of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
Presenting Author: Yitong Bian

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Novak I, Jackman M, Finch-Edmondson M, et al. Cerebral palsy. Lancet 2025; 406: 174-88.doi: 10.1016/S0140-6736(25)00686-5 [doi]
2. Jiang H, Li X, Jin C, et al. Early diagnosis of spastic cerebral palsy in infants with periventricular white matter injury using diffusion tensor imaging. AJNR Am J Neuroradiol 2019; 40: 162-68.doi: 10.3174/ajnr.A5914 [doi]
3. Raffelt DA, Tournier JD, Smith RE, et al. Investigating white matter fibre density and morphology using fixel-based analysis. Neuroimage 2017; 144: 58-73. doi: 10.1016/j.neuroimage.2016.09.029 [doi]
4. Pannek K, Fripp J, George JM, et al. Fixel-based analysis reveals alterations in brain microstructure and macrostructure of preterm-born infants at term equivalent age. NeuroImage Clin. 2018;18:51-59.doi: 10.1016/j.nicl.2018.01.003 [doi]
5. Grazioplene RG, Bearden CE, Subotnik KL, et al. Connectivity-enhanced diffusion analysis reveals white matter density disruptions in first episode and chronic schizophrenia. Neuroimage Clin 2018; 18: 608-16.doi: 10.1016/j.nicl.2018.02.015 [doi]
6. Dhollander T, Clemente A, Singh M, et al. Fixel-based analysis of diffusion MRI: methods, applications, challenges and future directions. Neuroimage 2021; 241: 118417.doi: 10.1016/j.neuroimage.2021.118417 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/669-02-012