Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
405-02-001 ISMRM Abstract

Four-year changes in white matter tract profiles characterize microstructural evolution in multiple sclerosis

Primary: Neuro - Multiple Sclerosis
Secondary: Analysis Methods - Visualization
405-02-001 · What's New in Multiple Sclerosis? · Tuesday, 12 May, 8:20 AM–10:10 AM · Ballroom West
Keywords: Multiple Sclerosis Tractography Fractional anisotropy Myelin water fraction
Accepted
Pantea Ghazanfari Moghadam1, Shannon Kolind 1, Elena Kovacevic1, Poljanka Johnson1, Erin Gallinger1, Irene M Vavasour1, Roger Tam1, Alex L MacKay1, David K Li2, Alexandre Prat3, Anthony Traboulsee1, Jiwon Oh4, Sharada Balaji1
1University of British Columbia, Vancouver, Canada
2Radiology, University of British Columbia, Vancouver, Canada
3University of Montreal, Montreal, Canada
4University of Toronto, Toronto, Canada
Presenting Author: Shannon Kolind

Synopsis

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References

1. MacKay A, Whittall K, Adler J, Li D, Paty D, Graeb D. In vivo visualization of myelin water in brain by magnetic resonance. Magn Reson Med. 1994;31(6):673–677. doi:10.1002/mrm.1910310614 [doi]
2. Pierpaoli C, Jezzard P, Basser PJ, Barnett A, Di Chiro G. Diffusion tensor MR imaging of the human brain. Radiology. 1996;201(3):637–648. doi:10.1148/radiology.201.3.8939209 [doi]
3. Jenkinson M, Beckmann CF, Behrens TEJ, Woolrich MW, Smith SM. FSL. Neuroimage. 2012;62(2):782–790. doi:10.1016/j.neuroimage.2011.09.015 [doi]
4. Doucette J, Kames C, Rauscher A. DECAES – DEcomposition and Component Analysis of Exponential Signals. Z Med Phys. 2020;30(4):336–348. doi:10.1016/j.zemedi.2020.04.001 [doi]
5. Wu A, Traboulsee A, Li DK, Tam R, Oh J, Vavasour I, Johnson P, Wiley N, Gallinger E, MacKay A, Kolind S, Balaji S. Quantifying longitudinal tract profile differences in multiple sclerosis lesional tracts. In: Proceedings of the 25th Annual Meeting of the International Society for Magnetic Resonance in Medicine; 2025; Honolulu, HI, USA. Abstract #3755.
6. Wasserthal J, Neher P, Maier-Hein KH. TractSeg: Fast and accurate white matter tract segmentation. Neuroimage. 2018;183:239–253. doi:10.1016/j.neuroimage.2018.07.070 [doi]
7. Balaji S, Dvorak AV, Wiley N, MacMillan EL, Traboulsee A, Vavasour IM, Gilbert G, Moore GRW, Li DKB, Kolind S. Myelin water and tensor-valued diffusion imaging: (How) are they related? Magn Reson Med. 2025;94(1):123–137. doi:10.1002/mrm.30620 [doi]

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http://echo.ismrm.org/p/ISMRM2026/405-02-001