Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
465-04-006 ISMRM Abstract

NMR and x-ray Advanced 2D/3D techniques to investigate 23Na relaxation and distribution concentration changes in AD

Primary: Neuro - Alzheimer's Disease
Secondary: Preclinical Animal & in vitro MR - Biology, Models, Methods
465-04-006 · Image Analysis for Alzheimer's and Parkinson's · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row F
Keywords: Alzheimer's Disease Relaxometry In vivo proton magnetic resonance spectroscopy Multimodal imaging Na23 MRI
Accepted
michela fratini1, Martina Negozio2, Alessandra Gianoncelli3, Fabrizio Bardelli4, Alessandra Maiuro2,5,6,7, Valentina Bonanni8, Benedetta Niccolini9,10, Elena Longo8, Giuliana Tromba8, Maria Guidi 11, Yasmine Salman12, Charles Nicaise13, Bernard HANSEEUW12, Giovanni Augusto Carlesimo14, Silvia Capuani15,16
1CNR-Nanotec &Santa Lucia Foundation, Rome, Italy
2Sapienza University of Rome, Rome, Italy
3Elettra Synchrotron, Trieste, Italy
4CNR-Nanotec, Rome, Italy
5Institute for complex systems, National Research Council (CNR), Rome, Italy
6Institute for complex systems (ISC), National Research Council (CNR), Rome, Italy
7CNR ISC, Rome, Italy
8Elettra-Sincrotrone Trieste, Trieste, Italy
9Fondazione Policlinico Universitario A. Gemelli, IRCSS, Roma, Italy
10IRCCS Fondazione Santa Lucia, Rome, Italy
11CREF - Museo storico della fisica e Centro studi e ricerche Enrico Ferm, Rome, Italy
12Cliniques universitaires Saint-Luc, Bruxelles, Belgium
13URPhyM–NARILIS, University of Namur, Belgium
14IRCCS Santa Lucia Foundation, Rome, Italy
15Complex Systems Institute, National Research Council (CNR), Rome, Italy
16Complex Systems Institute (ISC), National Research Council (CNR), Rome, Italy
Presenting Author: Maria Guidi

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References

1. Strazzullo, P., and C. Leclercq. "Sodium. Advances in Nutrition, 5 (2), 188–190 (2014)." doi.org: 10.3945/an.113.005215 [doi]
2. Nagel, Armin Michael, et al. Investigative radiology 46(9) 539-547 (2011). doi: 10.1097/RLI.0b013e31821ae918 [doi]
3. Madelin, Guillaume et al. (2013) Journal of Magnetic Resonance Imaging 38(3) 511 (2013) doi: 10.1002/jmri.24168 [doi]
4. Mellon, EA A., et al. "Sodium MR imaging detection of mild Alzheimer disease: preliminary study." American Journal of Neuroradiology 30.5 (2009): 978-984. doi: 10.1002/jmri.24168 [doi]
5. Sosa-Ortiz, Ana Luisa, Isaac Acosta-Castillo, and Martin J. Prince. "Epidemiology of dementias and Alzheimer’s disease." Archives of medical research 43.8 (2012): 600-608. doi:10.1016/j.arcmed.2012.11.003 [doi]

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http://echo.ismrm.org/p/ISMRM2026/465-04-006