Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
352-01-003 / 352-01-003 ISMRM Abstract

Boosting Sodium Signal in Interleaved 1H-MP2RAGE – 23Na-MERINA: A SAR-Constrained Optimisation Approach

Primary: Acquisition & Reconstruction - Pulse Sequence Design and Spatial Encoding Methods
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
352-01-003 · New Methods: Acquisition and Reconstruction · Monday, 11 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2
352-01-003 · New Methods: Acquisition and Reconstruction · Monday, 11 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2
Keywords: X-nuclei Multinuclear 23Na MRI Interleaved acquisition Ultra-high field (UHF) MRI
Accepted
Yasmin Blunck 1,2, Daniel Staeb3, Bradford A Moffat2,4, Rebecca Glarin2,4, Tudor V Sava2,4, Kieran R O'Brien3,5, Leigh Johnston1,2
1Department of Biomedical Engineering and Graeme Clark Institute, University of Melbourne, Melbourne, Australia
2Melbourne Brain Centre Imaging Unit, University of Melbourne, Melbourne, Australia
3MR Research Collaborations, Siemens Healthcare Pty Ltd, Brisbane, Australia
4Department of Radiology, University of Melbourne, Melbourne, Australia
5Australian Institute for Bioengineering and Nanotechnology, Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia
Presenting Author: Yasmin Blunck

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Thulborn, K. R. (2018). Quantitative sodium MR imaging: a review of its evolving role in medicine. Neuroimage, 168, 250-268. doi:10.1016/j.neuroimage.2016.11.056 [doi]
2. Lopez Kolkovsky, A. L., Carlier, P. G., Marty, B., & Meyerspeer, M. (2022). Interleaved and simultaneous multi‐nuclear magnetic resonance in vivo. Review of principles, applications and potential. NMR in Biomedicine, 35(10), e4735. doi:10.1002/nbm.4735 [doi]
3. Marques, J. P., Kober, T., Krueger, G., van der Zwaag, W., Van de Moortele, P. F., & Gruetter, R. (2010). MP2RAGE, a self bias-field corrected sequence for improved segmentation and T1-mapping at high field. Neuroimage, 49(2), 1271-1281. doi:10.1016/j.neuroimage.2009.10.002 [doi]
4. Blunck, Y., Staeb, D., Glarin, R. K., Moffat, B. A., O'Brien, K., & Johnston, L. A. Multiplexed Measurement of Multiple Nuclei (M3N) for integrated multi-nuclei imaging and parametric mapping in 23Na and 1H MRI. In Proceedings of the 28th Annual Meeting of the ISMRM (2020). Virtual Conference and Exhibition. p.474 doi: https://archive.ismrm.org/2020/0474.html
5. Blunck, Y., Josan, S., Taqdees, S. W., Moffat, B. A., Ordidge, R. J., Cleary, J. O., & Johnston, L. A. (2018). 3D-multi-echo radial imaging of 23Na (3D-MERINA) for time-efficient multi-parameter tissue compartment mapping. Magnetic resonance in medicine, 79(4), 1950-1961. https://doi.org/10.1002/mrm.26848 [doi]
6. Wu, C., Blunck, Y., & Johnston, L. A. (2022). The “spin‐3/2 Bloch equation”: system matrix formalism of excitation, relaxation, and off‐resonance effects in biological tissue. Magnetic Resonance in Medicine, 88(3), 1370-1379. https://doi.org/10.1002/mrm.29276 [doi]
7. Moffat, B. A., Glarin, R., Blunck, Y., Sava, T. A., Green, E., Berangi, M., ... & Johnston, L. A. Sodium and Proton Knee MRI using a 32 Channel Transmit and Receive Modular Array at 7.0 Tesla. In Proceedings of the 32nd Annual Meeting of the ISMRM (2024). Singapore. p.1444. https://doi.org/10.58530/2024/1444 [doi]
8. Wu, M., Cleary, J., Bridgen, P., Di Cio, P., McElroy, S., Rot, S., ... & Ipek, Ö. Towards time-efficient sodium and proton MRI at 7T. In Proceedings of the 33rd Annual Meeting of the ISMRM (2025). Honolulu, HI, USA. p.1181 https://doi.org/10.58530/2025/1181 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/352-01-003