Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
364-02-009 ISMRM Abstract

The combination of ASL and quantitative synthetic MRI for predicting IDH1 gene mutation in glioma patients

Primary: Neuro - Tumors
Secondary: Contrast Mechanisms - Arterial Spin Labelling
364-02-009 · Innovations in Brain Tumor Imaging: Quantitative MRI, Radiogenomics, and Deep-Learning Approaches · Monday, 11 May, 9:15 AM–10:10 AM · Digital Posters Row E
Keywords: MR Fingerprinting/Synthetic MR Arterial spin labelling Glioma IDH mutation
Accepted
Dan Luo 1, Jiankun Dai2, Zexiang Deng1, Xinru Deng1, Xinlan Xiao1
1Department of Radiology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
2MR Research, Beijing, China
Presenting Author: Dan Luo

Synopsis

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References

1. SEJDA A, GRAJKOWSKA W, TRUBICKA J, et al. WHO CNS5 2021 classification of gliomas: a practical review and road signs for diagnosing pathologists and proper patho-clinical and neuro-oncological cooperation[J].Folia Neuropathol,2022,60(2):137-152.DOI:10.5114/fn.2022.118183. [doi]
2. ALSHIEKH NASANY R, de la FUENTE M I. Therapies for IDH-Mutant Gliomas[J].Curr Neurol Neurosci Rep,2023,23(5):225-233.DOI:10.1007/s11910-023-01265-3. [doi]
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6. CHEN S, DAI J, ZHAO J, et al. Synthetic MRI Combined With Clinicopathological Characteristics for Pretreatment Prediction of Chemoradiotherapy Response in Advanced Nasopharyngeal Carcinoma[J].Korean J Radiol,2025,26(2):135-145.DOI:10.3348/kjr.2024.0385. [doi]
7. NARANG J, JAIN R, SCARPACE L, et al. Tumor vascular leakiness and blood volume estimates in oligodendrogliomas using perfusion CT: an analysis of perfusion parameters helping further characterize genetic subtypes as well as differentiate from astroglial tumors[J].J Neurooncol,2011,102(2):287-293.DOI:10.1007/s11060-010-0317-3. [doi]
8. ZHANG L, HE L, LUGANO R, et al. IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas[J].Neuro Oncol,2018,20(11):1505-1516.DOI:10.1093/neuonc/noy088. [doi]
9. GE X, WANG M, MA H, et al. Investigated diagnostic value of synthetic relaxometry, three-dimensional pseudo-continuous arterial spin labelling and diffusion-weighted imaging in the grading of glioma[J].Magn Reson Imaging,2022,86:20-27.DOI:10.1016/j.mri.2021.11.006. [doi]

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http://echo.ismrm.org/p/ISMRM2026/364-02-009