Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
362-02-003 ISMRM Abstract

Time-Dependent Diffusion MRI–Based Microstructural Mapping for Predicting IDH Mutation Status in Glioma: A Multicenter Study

Primary: Neuro - Tumors
Secondary: Diffusion - Microstructure
362-02-003 · Clinical Diffusion Neuro · Monday, 11 May, 9:15 AM–10:10 AM · Digital Posters Row C
Keywords: Glioma Histogram Td-dMRI
Accepted
Wanjun Hu 1, Darui Li2, Yuhui Xiong3, Lizhi Xie3,4,5,6,7, Jing Zhang8,9,10,11
1The Second Hospital & Clinical Medical School, Lanzhou, China
2Department of Magnetic Resonance,, Department of Magnetic Resonance, Lanzhou, China
3GE HealthCare MR Research, Beijing, China
4GE Healthcare, Beijing, China
5GE Healthcare, Beijing, China
6GE Healthcare, MR Research China, Beijing, 100176, P.R. China, China
7MRI Research, GE Healthcare, Beijing, China
8The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, China
9Department of Magnetic Resonance, Lanzhou, China
10Gansu Province Clinical Research Center for Functional and Molecular Imaging, Lanzhou, China, Department of Magnetic Resonance, Lanzhou, China
11Gansu Province Clinical Research Center for Functional and Molecular Imaging, Lanzhou, China, Department of Magnetic Resonance, Lanzhou, China
Presenting Author: Wanjun Hu

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References

1. Louis DN, Perry A, Wesseling P, et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro-Oncology 2021;23(8):1231-1251.
2. Rudà R, Horbinski C, van den Bent M, Preusser M, Soffietti R. IDH inhibition in gliomas: from preclinical models to clinical trials. Nature Reviews Neurology 2024;20(7):395-407.
3. Li G, Li L, Li Y, et al. An MRI radiomics approach to predict survival and tumour-infiltrating macrophages in gliomas. Brain 2022;145(3):1151-1161.
4. Moon HH, Park JE, Kim N, et al. Prospective longitudinal analysis of physiologic MRI-based tumor habitat predicts short-term patient outcomes in IDH-wildtype glioblastoma. Neuro-Oncology 2025;27(3):841-853.
5. Wu D, Jiang K, Li H, et al. Time-Dependent Diffusion MRI for Quantitative Microstructural Mapping of Prostate Cancer. Radiology 2022;303(3):578-587.
6. Jiang X, Li H, Xie J, et al. In vivo imaging of cancer cell size and cellularity using temporal diffusion spectroscopy. Magnetic Resonance in Medicine 2016;78(1):156-164.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/362-02-003