Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
361-03-009 ISMRM Abstract

Rapid Gradient-Echo 7 Tesla EPI of Cardiac Pulsatility Arrival Time and Amplitude Across Arterial and Ventricular Regions

Primary: Neuro - Neurofluids
Secondary: Contrast Mechanisms - Velocity/Flow
361-03-009 · Thermometry and Other Contrast Mechanisms · Monday, 11 May, 1:50 PM–2:45 PM · Digital Posters Row B
Keywords: Choroid plexus Neurofluid dynamics Cardiac pulsatility Fast 7 Tesla EPI Brain compliance and glymphatics
Accepted
Firdaus Fabrice Hannanu1, Marta Bianciardi 1,2
1Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America
2Division of Sleep Medicine, Harvard University, Cambridge, United States of America
Presenting Author: Marta Bianciardi

Synopsis

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References

1. Iliff JJ, Wang M, Zeppenfeld DM, Venkataraman A, Plog BA, Liao Y, Deane R, Nedergaard M. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain. J Neurosci. 2013 Nov 13;33(46):18190-9. doi: 10.1523/JNEUROSCI.1592-13.2013. PMID: 24227727; PMCID: PMC3866416. [doi] [pmid]
2. Vikner T, Johnson KM, Cadman RV, Betthauser TJ, Wilson RE, Chin N, Eisenmenger LB, Johnson SC, Rivera-Rivera LA. CSF dynamics throughout the ventricular system using 4D flow MRI: associations to arterial pulsatility, ventricular volumes, and age. Fluids Barriers CNS. 2024 Aug 30;21(1):68. doi: 10.1186/s12987-024-00570-4. PMID: 39215377; PMCID: PMC11363656. [doi] [pmid]
3. Wagshul ME, Chen JJ, Egnor MR, McCormack EJ, Roche PE. Amplitude and phase of cerebrospinal fluid pulsations: experimental studies and review of the literature. J Neurosurg. 2006 May;104(5):810-9. doi: 10.3171/jns.2006.104.5.810. PMID: 16703889. [doi] [pmid]
4. Rajna Z, Mattila H, Huotari N, Tuovinen T, Krüger J, Holst SC, Korhonen V, Remes AM, Seppänen T, Hennig J, Nedergaard M, Kiviniemi V. Cardiovascular brain impulses in Alzheimer's disease. Brain. 2021 Aug 17;144(7):2214-2226. doi: 10.1093/brain/awab144. Erratum in: Brain. 2021 Nov 29;144(10):e86. doi: 10.1093/brain/awab298. PMID: 33787890; PMCID: PMC8422353. [doi] [pmid]
5. Bianciardi M, Toschi N, Polimeni JR, Evans KC, Bhat H, Keil B, Rosen BR, Boas DA, Wald LL. The pulsatility volume index: an indicator of cerebrovascular compliance based on fast magnetic resonance imaging of cardiac and respiratory pulsatility. Philos Trans A Math Phys Eng Sci. 2016 May 13;374(2067):20150184. doi: 10.1098/rsta.2015.0184. PMID: 27044992; PMCID: PMC4822444. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/361-03-009