Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
462-03-011 ISMRM Abstract

Poroelastic Inversion of the Human Brain at 3T using Amplified MRI

Primary: Neuro - Neurofluids
Secondary: Contrast Mechanisms - Elastography
462-03-011 · Heart and Brain Axis · Tuesday, 12 May, 1:40 PM–2:35 PM · Digital Posters Row C
Keywords: Cardiac Cine MRI Magnetic Resonance Elastography Intrinsic MR elastography 3D aMRI Poroelastic non-linear inversion
Accepted
Tyson Lam 1, Patrick Fillingham2, Matthew McGarry3, Caitlin M Neher1, Em R Triolo4,5, Fargol RezayAraghi1, Mehmet Kurt1,6
1Mechanical Engineering, University of Washington, Seattle, United States of America
2Department of Neurology, University of Washington, Seattle, United States of America
3Thayer School of Engineering, Dartmouth College, Hanover, United States of America
4Radiology, Children's Hospital of Philadelphia, Philadelphia, United States of America
5Children's Hospital of Philadelphia, Philadelphia, United States of America
6University of Washington, Seattle, United States of America
Presenting Author: Tyson Lam

Synopsis

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References

1. [1] Adams, A. L., Viergever, M. A., Luijten, P. R., & Zwanenburg, J. J. M. (2020). Validating faster DENSE measurements of cardiac-induced brain tissue expansion as a potential tool for investigating cerebral microvascular pulsations. NeuroImage, 208, 116466. https://doi.org/10.1016/j.neuroimage.2019.116466 [doi]
2. [2] Abderezaei, J., Pionteck, A., Terem, I., Dang, L., Scadeng, M., Morgenstern, P., Shrivastava, R., Holdsworth, S. J., Yang, Y., & Kurt, M. (2021). Development, calibration, and testing of 3D amplified MRI (aMRI) for the quantification of intrinsic brain motion. Brain Multiphysics, 2, Article 100022. https://doi.org/10.1016/j.brain.2021.100022 [doi]
3. [3] Terem, I., Dang, L., Champagne, A., Abderezaei, J., Pionteck, A., Almadan, Z., Lydon, A.-M., Kurt, M., Scadeng, M., & Holdsworth, S. J. (2021). 3D amplified MRI (aMRI). Magnetic Resonance in Medicine, 86(3), 1674-1686. https://doi.org/10.1002/mrm.28797 [doi]
4. [4] McGarry, M. D., Johnson, C. L., Sutton, B. P., Georgiadis, J. G., Van Houten, E. E., Pattison, A. J., Weaver, J. B., & Paulsen, K. D. (2015). Suitability of poroelastic and viscoelastic mechanical models for high and low frequency MR elastography. Medical physics, 42(2), 947–957. https://doi.org/10.1118/1.4905048 [doi]
5. [5] Abderezaei, J., Rezayaraghi, F., Pionteck, A., et al. (2024). Increased hindbrain motion in Chiari I malformation patients measured through 3D amplified MRI (3D aMRI). Brain Multiphysics, 7(8), 100100. https://doi.org/10.1016/j.brain.2024.100100 [doi]
6. [7] McGarry, M., Johnson, C. L., Sutton, B. P., Van Houten, E. E., Georgiadis, J. G., Weaver, J. B., & Paulsen, K. D. (2013). Including spatial information in nonlinear inversion MR elastography using soft prior regularization. IEEE Transactions on Medical Imaging, 32(10), 1901-1909. https://doi.org/10.1109/TMI.2013.2268978 [doi]
7. Triolo, E., Khegai, O., McGarry, M., Lam, T., Veraart, J., Alipour, A., Balchandani, P., & Kurt, M. (2024). Characterizing brain mechanics through 7 tesla magnetic resonance elastography. Physics in medicine and biology, 69(20), 10.1088/1361-6560/ad7fc9. https://doi.org/10.1088/1361-6560/ad7fc9 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/462-03-011