463-02-001 ISMRM Abstract

Can DKI and EPT analysis reflecting voxel-wise heterogeneity capture subtle tissue changes after stroke stem cell therapy?

Primary: Neuro - Stroke and Cerebrovascular Disorders

Secondary: Contrast Mechanisms - Electromagnetic Tissue Properties

463-02-001 · Imaging Stroke Recovery: From Microstructure to Personalized Therapy · Tuesday, 12 May, 9:15 AM–10:10 AM · Digital Posters Row D

Keywords: Radiomics DKI Electric properties tomography Cerebral infarction Stem cell transplantation

Accepted

Maho Kitagawa ^1,2,3, Masahito Kawabori⁴, Xinnan Li², Ulrich Katscher⁵, Khin Khin Tha^1,2,6,7

¹Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, Sappro, Japan

²Laboratory for Biomarker Imaging Science, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sappro, Japan

³Office for Developing Future Research Leaders, Institute for Integrated Innovations, Hokkaido University, Sappro, Japan

⁴Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Hokkaido University, Sappro, Japan

⁵Philips Innovative Technologies, Hamburg, Germany

⁶Faculty of Medicine, Hokkaido University, Sappro, Japan

⁷Global Center for Biomedical Scienec and Engineering, Faculty of Medicine, Hokkaido University, Sappro, Japan

Presenting Author: Maho Kitagawa

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References

1. Di Carlo A. Human and economic burden of stroke. Age Ageing. 2009;38(1):4-5.

2. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, & Chopp M. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke. 2001;32(4):1005-1011.

3. Bang OY, Lee JS, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol. 2005;57(6):874-882.

4. Liu YF, Liu HT, Chang C, Yang CX, Liu XN, Wang X, Ge W, Wang RZ, & Bao XJ. Stereotactically intracerebral transplantation of neural stem cells for ischemic stroke attenuated inflammatory responses and promoted neurogenesis: an experimental study with monkeys. Int J Surg. 2024;110(9):5417-5433.

5. Tha KK, Katscher U, Hamaguchi H, Li X, Kawasaki T, Yamaguchi S, Yabe I, Hyodoh H. The Role of Electric Properties Tomography in Biochemical Analysis of the Cerebrospinal Fluid and Parameter Optimization for Improved Accuracy. Proc. Intl. Soc. Mag. Reson. Med. 30 (2022) 3648. Joint Annual Meeting ISMRM-ESMRMB.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/463-02-001