Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
451-02-002 / 451-02-002 ISMRM Abstract

Visually stimulated functional Deuterium Metabolic Imaging (DMI following [2H2] and [2H7] glucose ingestion

Primary: Contrast Mechanisms - Deuterium
Secondary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging
451-02-002 · Advances in Contrast Mechanisms · Tuesday, 12 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
451-02-002 · Advances in Contrast Mechanisms · Tuesday, 12 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
Keywords: Deuterium Metabolic Imaging Functional spectroscopy
Accepted
Max A Espley 1,2, Daniel J Cocking2,3, Robin Damion2, Dorothee P Auer1,2, Richard Bowtell2
1NIHR Nottingham Biomedical Research Centre, Queen’s Medical Centre, Nottingham, United Kingdom
2Sir Peter Mansfield Imaging Center, University of Nottingham, Nottingham, United Kingdom
3School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom
Presenting Author: Max A Espley

Synopsis

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References

1. De Feyter, H. M., & de Graaf, R. A. (2021). Deuterium metabolic imaging–Back to the future. Journal of Magnetic Resonance, 326, 106932. DOI: 10.1016/j.jmr.2021.106932 [doi]
2. Pan, F., Liu, X., Wan, J., Guo, Y., Sun, P., Zhang, X., ... & Yang, L. (2024). Advances and prospects in deuterium metabolic imaging (DMI): a systematic review of in vivo studies. European Radiology Experimental, 8(1), 65. DOI: 10.1186/s41747-024-00464-y [doi]
3. Mahar, R., Zeng, H., Giacalone, A., Ragavan, M., Mareci, T. H., & Merritt, M. E. (2021). Deuterated water imaging of the rat brain following metabolism of [2H7] glucose. Magnetic resonance in medicine, 85(6), 3049-3059. DOI: 10.1002/mrm.28700 [doi]
4. Cocking, D., Damion, R., Simpson, E., Greenhaff, P., Dexter, L., Auer, D., & Bowtell, R. Comparison of deuterium metabolic imaging measurements in human subjects at 7T following [2 H 2] glucose and [2 H 7] glucose ingestion. ISMRM 2023. DOI:10.58530/2023/0015 [doi]
5. Purvis, L. A., Clarke, W. T., Biasiolli, L., Valkovič, L., Robson, M. D., & Rodgers, C. T. (2017). OXSA: an open-source magnetic resonance spectroscopy analysis toolbox in MATLAB. PloS one, 12(9), e0185356. DOI:10.1371/journal.pone.0185356 [doi]
6. Govindaraju, V., Young, K., & Maudsley, A. A. (2000). Proton NMR chemical shifts and coupling constants for brain metabolites. NMR in biomedicine: an international journal devoted to the development and application of magnetic resonance in vivo, 13(3), 129-153. DOI: 10.1002/1099-1492(200005)13:3<129::aid-nbm619>3.0.co;2-v [doi]
7. Smith, S. M. (2002). Fast robust automated brain extraction. Human brain mapping, 17(3), 143-155. DOI: 10.1002/hbm.10062 [doi]

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http://echo.ismrm.org/p/ISMRM2026/451-02-002