Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
569-03-009 ISMRM Abstract

Beyond the Plane: Multi-Planar Super-Resolution MRI Improves 3D Spinal Cord Lesion Assessment

Primary: Neuro - Spinal Cord
Secondary: Acquisition & Reconstruction - Quantitative Imaging: spine, MSK, others
569-03-009 · Super-Resolving MRI: Methods and Applications · Wednesday, 13 May, 1:40 PM–2:35 PM · Digital Posters Row J
Keywords: Spinal Cord Toolbox Spinal cord injury Spinal cord lesions Super-resolution reconstruction Spinal cord imaging
Accepted
Tim M Emmenegger 1, Steffen Franz2, Michael Adam1,3, Anna Duguid1, Patrick Will1, Simon Schading-Sassenhausen4, Bernhard Strasser1, Sabina Frese1, Wolfgang Marik5,6, Wolfgang Bogner1,3,7, Simon Robinson1,3
1High Field Magnetic Resonance Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria
2Department for Spinal Cord Injury, AUVA Rehabilitation Center Weisser Hof, Klosterneuburg, Austria, Austria
3Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Austria, Austria
4Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland, Switzerland
5Comprehensive Center for Clinical Neurosciences & Mental Health,, Medical University of Vienna, Vienna, Austria, Austria
6Department of Neuroradiology, Medical University of Vienna, Vienna, Austria, Austria
7Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, Vienna, Austria
Presenting Author: Tim M Emmenegger

Synopsis

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References

1. Emmenegger TM, Pfyffer D, Curt A, et al. Longitudinal motor system changes from acute to chronic spinal cord injury. Eur J Neurol. 2024;(October 2023):1-12. doi:10.1111/ene.16196 [doi]
2. Pfyffer D, Smith AC, Weber KA, et al. Prognostic value of tissue bridges in cervical spinal cord injury: a longitudinal, multicentre, retrospective cohort study. Lancet Neurol. Published online June 2024. doi:10.1016/S1474-4422(24)00173-X [doi]
3. Farner L, Emmenegger TM, Schading‐Sassenhausen S, et al. 3D MRI Tract‐Specific Spinal Cord Lesion Pattern Improves Prediction of Distinct Neurological Recovery. Ann Clin Transl Neurol. Published online June 27, 2025. doi:10.1002/acn3.70087 [doi]
4. Smith AC, O’Dell DR, Albin SR, et al. Lateral Corticospinal Tract and Dorsal Column Damage: Predictive Relationships With Motor and Sensory Scores at Discharge From Acute Rehabilitation After Spinal Cord Injury. Arch Phys Med Rehabil. 2022;103(1):62-68. doi:10.1016/j.apmr.2021.07.792 [doi]
5. Smith AC, Weber KA, O’Dell DR, Parrish TB, Wasielewski M, Elliott JM. Lateral Corticospinal Tract Damage Correlates With Motor Output in Incomplete Spinal Cord Injury. Arch Phys Med Rehabil. 2018;99(4):660-666. doi:10.1016/j.apmr.2017.10.002 [doi]
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7. Bachrata B, Bollmann S, Jin J, et al. Super-resolution QSM in little or no additional time for imaging (NATIve) using 2D EPI imaging in 3 orthogonal planes. Neuroimage. 2023;283:120419. doi:10.1016/j.neuroimage.2023.120419 [doi]
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9. De Leener B, Lévy S, Dupont SM, et al. SCT: Spinal Cord Toolbox, an open-source software for processing spinal cord MRI data. Neuroimage. 2017;145(March 2016):24-43. doi:10.1016/j.neuroimage.2016.10.009 [doi]
10. Enamundram NK, Valošek J, Farner L, et al. SCIsegV2: A Universal Tool for Segmentation of Intramedullary Lesions in Spinal Cord Injury. In: 2025:198-209. doi:10.1007/978-3-031-82007-6_19 [doi]
11. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986;1(8476):307-310. doi:10.1128/AAC.00483-18 [doi]
12. Henmar S, Simonsen EB, Berg RW. What are the gray and white matter volumes of the human spinal cord? J Neurophysiol. 2020;124(6):1792-1797. doi:10.1152/jn.00413.2020 [doi]
13. Valošek J, Bédard S, Keřkovský M, Rohan T, Cohen-Adad J. A database of the healthy human spinal cord morphometry in the PAM50 template space. Preprint posted online October 17, 2023. doi:10.55458/neurolibre.00017 [doi]

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http://echo.ismrm.org/p/ISMRM2026/569-03-009