Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
331-03-005 / 331-03-005 ISMRM Abstract

Genotype-Stratified Default Mode Network Hyperconnectivity as an Endophenotype of MDD: an MR imaging genetics study

Accepted
Paramdeep Singh 1
1Radiology, All India Institute of Medical Sciences, New Delhi, India
Presenting Author: Paramdeep Singh

Synopsis

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References

1. Cui L, Li S, Wang S, Wu X, Liu Y, Yu W, et al. Major depressive disorder: hypothesis, mechanism, prevention and treatment. Signal Transduct Target Ther. 2024 Feb 9;9(1):30.
2. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 - Google Search [Internet]. [cited 2025 Sept 2]. Available from: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00757-8/fulltext
3. Liu J, Ye Z, Cai Y, Li J, Dong Z, Zhang X, et al. Unmasking the rising global burden of depression: A 32-year GBD analysis of gender disparities and regional hotspots in Sub-Saharan Africa. Ye P, editor. PLOS One. 2025 July 31;20(7):e0326974.
4. Murthy Rs. National mental health survey of India 2015–2016. Indian J Psychiatry. 2017;59(1):21.
5. Remes O, Mendes JF, Templeton P. Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature. Brain Sci. 2021 Dec 10;11(12):1633.
6. Cai H, Xie XM, Zhang Q, Cui X, Lin JX, Sim K, et al. Prevalence of Suicidality in Major Depressive Disorder: A Systematic Review and Meta-Analysis of Comparative Studies. Front Psychiatry. 2021 Sept 16;12:690130.
7. Chand SP, Arif H. Depression. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 [cited 2025 Sept 1]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK430847/
8. Bains N, Abdijadid S. Major Depressive Disorder. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 [cited 2025 Sept 1]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK559078/
9. DSM Library [Internet]. [cited 2025 Sept 1]. Diagnostic and Statistical Manual of Mental Disorders | Psychiatry Online. Available from: https://psychiatryonline.org/doi/book/10.1176/appi.books.9780890425787
10. National Research Council (US) and Institute of Medicine (US) Committee on Depression PP, England MJ, Sim LJ. The Etiology of Depression. In: Depression in Parents, Parenting, and Children: Opportunities to Improve Identification, Treatment, and Prevention [Internet]. National Academies Press (US); 2009 [cited 2025 Sept 1]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK215119/

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