Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
366-05-004 ISMRM Abstract

Time-Resolved Multiecho 4D MRI for Robust Free-Breathing PDFF and R2* Quantification Across Field Strengths

Primary: Body - Liver
Secondary: Acquisition & Reconstruction - Motion Correction: Non-Neuro
366-05-004 · Quantitative Applications in Body MRI: Make the Numbers Count · Monday, 11 May, 4:10 PM–5:05 PM · Digital Posters Row G
Keywords: Liver Proton density fat fraction (PDFF) R2star mapping Field strength comparison Motion detection and correction
Accepted
Jeffery Wong 1,2,3,4, Jingjia Chen1,3,4, Ding Xia5,6, Els Fieremans1,3,4, Dmitry S Novikov1,3,4, Hersh Chandarana1,3,4, Li Feng1,3,4
1Department of Radiology, New York University Grossman School of Medicine, New York, United States of America
2Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, United States of America
3Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, United States of America
4Center for Advanced Imaging Innovation and Research (CAI²R), New York University Grossman School of Medicine, New York, United States of America
5BioMedical Engineering and Imaging Institute (BMEII), Icahn School of Medicine at Mount Sinai, New York, United States of America
6Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York, United States of America
Presenting Author: Jeffery Wong

Synopsis

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References

1. Zhong X, Armstrong T, Nickel MD, et al. Effect of respiratory motion on free-breathing 3D stack of-radial liver relaxometry and improved quantification accuracy using self-gating. Magn Reson Med. 2020; 83: 1964–1978. https://doi.org/10.1002/mrm.28052 [doi]
2. Shih SF, Wu HH. Free-breathing MRI techniques for fat and R2* quantification in the liver. MAGMA. 2024 Aug;37(4):583-602. doi: 10.1007/s10334-024-01187-2. Epub 2024 Jul 23. PMID: 39039272; PMCID: PMC11878285. [doi] [pmid]
3. Feng L, Wen Q, Huang C, Tong A, Liu F, Chandarana H. GRASP-Pro: imProving GRASP DCE-MRI through self-calibrating subspace-modeling and contrast phase automation. Magn Reson Med. 2020 Jan;83(1):94-108. doi: 10.1002/mrm.27903. Epub 2019 Aug 10. PMID: 31400028; PMCID: PMC6778712. [doi] [pmid]
4. Benkert T, Tian Y, Huang C, DiBella EVR, Chandarana H, Feng L. Optimization and validation of accelerated golden-angle radial sparse MRI reconstruction with self-calibrating GRAPPA operator gridding. Magn Reson Med. 2018 Jul;80(1):286-293. doi: 10.1002/mrm.27030. Epub 2017 Nov 28. PMID: 29193380; PMCID: PMC5876102. [doi] [pmid]
5. Chen J, Huang C, Shanbhogue K, Xia D, Bruno M, Huang Y, Block KT, Chandarana H, Feng L. DCE-MRI of the liver with sub-second temporal resolution using GRASP-Pro with navi-stack-of-stars sampling. NMR Biomed. 2024 Dec;37(12):e5262. doi: 10.1002/nbm.5262. Epub 2024 Sep 25. PMID: 39323100; PMCID: PMC11998610. [doi] [pmid]
6. Feng L. Live-view 4D GRASP MRI: A framework for robust real-time respiratory motion tracking with a sub-second imaging latency. Magn Reson Med. 2023 Sep;90(3):1053-1068. doi: 10.1002/mrm.29700. Epub 2023 May 19. PMID: 37203314; PMCID: PMC10330383. [doi] [pmid]
7. Hernando D, Kellman P, Haldar JP, Liang ZP. Robust water/fat separation in the presence of large field inhomogeneities using a graph cut algorithm. Magn Reson Med. 2010 Jan;63(1):79-90. doi: 10.1002/mrm.22177. PMID: 19859956; PMCID: PMC3414226. [doi] [pmid]
8. C.-Y. Liu, C. A. McKenzie, H. Yu, J. H. Brittain, and S. B. Reeder, “Fat quantification with IDEAL gradient echo imaging: Correction of bias from T1 and noise,” Magnetic Resonance in Medicine, vol. 58, no. 2, pp. 354–364, 2007, doi: 10.1002/mrm.21301. [doi]

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http://echo.ismrm.org/p/ISMRM2026/366-05-004