Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-02-014 ISMRM Abstract

Microstructural MRI of the fetal brain: preliminary observations from in utero DTI and magnetization transfer imaging

Primary: Contrast Mechanisms - Magnetization Transfer
Secondary: Pediatrics - Fetal
663-02-014 · Diffusion: DWI/DTI/DKI · Thursday, 14 May, 9:25 AM–10:20 AM · Digital Posters Row D
Keywords: Magnetization transfer Neurodevelopment Fetal MRI Diffusion Tensor Imaging (DTI)
Accepted
Siddharth Sadanand 1, Rob Stobbe2, Shiri Shinar3,4,5, Tim van Mieghem3,4,5, Elka Miller6,7, Pradeep Krishnan6,7, Greg Stanisz8,9, Dafna Sussman1,9
1Electrical, Computer and Biomedical Engineering, Toronto Metropolitan University, Toronto, Canada
2Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada
3Institute of Medical Science, University of Toronto, Toronto, Canada
4Department of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, Canada
5Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Canada
6Department of Medical Imaging, University of Toronto, Toronto, Canada
7Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Canada
8Department of Physical Sciences, Sunnybrook Research Institute, Toronto, Canada
9Department of Medical Biophysics, University of Toronto, Toronto, Canada
Presenting Author: Siddharth Sadanand

Synopsis

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References

1. Welsh RC, Nemec U, Thomason ME. Fetal magnetic resonance imaging at 3.0T. Topics in MRI. 2011;22(3):119-131. doi:10.1097/RMR.0b013e318267f932 [doi]
2. Vavasour IM, Whittall KP, Mackay AL, et al. A comparison between magnetization transfer ratios and myelin water percentages in normals and multiple sclerosis patients. Magn. Reson. Med. 1998;40(5):763-768. doi:10.1002/mrm.1910400518 [doi]
3. Jones KM, Pollard AC, Pagel MD. Clinical applications of chemical exchange saturation transfer (CEST) MRI. JMR. 2018;47(1):11-27. doi:10.1002/jmri.25838 [doi]
4. S. Sadanand et al., “Magnetization transfer MRI of third trimester fetal brain: a pilot of gestational myelin imaging,” Front. Pediatr., vol. 13, May 2025. doi:10.3389/fped.2025.1443387. [doi]
5. S. Perlman, D. Shashar, C. Hoffmann, O. B. Yosef, R. Achiron, and E. Katorza, “Prenatal Diagnosis of Fetal Ventriculomegaly: Agreement between Fetal Brain Ultrasonography and MR Imaging,” American Journal of Neuroradiology, vol. 35, no. 6, pp. 1214–1218, June 2014, doi: 10.3174/ajnr.A3839. [doi]
6. U. M. Reddy, R. A. Filly, and J. A. Copel, “Prenatal Imaging: Ultrasonography and Magnetic Resonance Imaging,” p. 20, 2009. doi:10.1097/01.AOG.0000318871.95090.d9 [doi]
7. G. Sinson et al., “Magnetization Transfer Imaging and Proton MR Spectroscopy in the Evaluation of Axonal Injury: Correlation with Clinical Outcome after Traumatic Brain Injury,” 2001.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-02-014