Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
663-03-006 ISMRM Abstract

Diffusion along the perivascular space may serve as a biomarker to differentiate glioma recurrence from pseudoprogression

Primary: Neuro - Tumors
Secondary: Diffusion - DWI/DTI/DKI
663-03-006 · Glymphatic System Imaging: From Neurofluid Transport to Neurodegeneration · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row D
Keywords: Glioma DTI-ALPS Recurrence Diffusion Tensor Imaging (DTI) Glymphatic system (GS)
Accepted
Xiaoyi Wu 1, Qinxi Luo1, Mai Zhang1, Chengmin Su1, Yiming Wang2, Yuankui Wu1
1Department of Diagnostic Imaging, Nanfang Hospital, Southern Medical University, Guangzhou, China
2Bayer Healthcare Company Limited, Guangzhou, China
Presenting Author: Xiaoyi Wu

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Wu X, Zhang M, Jiang Q, Li M, Wu Y. Diagnostic accuracy of magnetic resonance diffusion tensor imaging in distinguishing pseudoprogression from glioma recurrence: A systematic review and meta-analysis.Expert Rev Anticancer Ther 2024;24:1177-1185. DOI:10.1080/14737140.2024.2415404 [doi]
2. Zhu H, Xie Y, Li L, Liu Y, Li S, Shen N, Zhang J, Yan S, Liu D, Li Y, Zhu W. Diffusion along the perivascular space as a potential biomarker for glioma grading and isocitrate dehydrogenase 1 mutation status prediction. Quant Imaging Med Surg 2023;13:8259-8273. DOI: 10.21037/qims-23-541 [doi]
3. Wang L, Liu L, Zhang H, Yue Q. Diffusion tensor imaging changes along the perivascular spaces may serve as a prognostic factor for high-grade glioma. Eur J Radiol 2025;184:111993. DOI: 10.1016/j.ejrad.2025.111993 [doi]
4. Fang K, Wang C, Zhang Y, Wu S, Liu L, Wen X. Noninvasive assessment of glymphatic dysfunction and IDH mutation in glioma with DTI-ALPS and DTI metrics. Quant Imaging Med Surg 2025;15:5007-5022.DOI: 10.21037/qims-2024-2710 [doi]
5. Zeng S, Huang Z, Zhou W, Ma H, Wu J, Zhao C, Yang Z, Qiu H, Chu J. Noninvasive evaluation of the glymphatic system in diffuse gliomas using diffusion tensor image analysis along the perivascular space. J Neurosurg 2025;142:187-196. DOI: 10.3171/2024.4.JNS232724 [doi]
6. Liang W, Sun W, Li C, Zhou J, Long C, Li H, Xu D, Xu H. Glymphatic system dysfunction and cerebrospinal fluid retention in gliomas: Evidence from perivascular space diffusion and volumetric analysis. Cancer Imaging 2025;25:51.DOI: 10.1186/s40644-025-00868-y [doi]
7. Scalia G, Ferini G, Silven MP, Noto M, Costanzo R, Maugeri R, Iacopino DG, Zagardo V, Viola A, Nicoletti GF, Umana GE. Alterations of the glymphatic system in glioblastomas: A systematic review. Anticancer Res 2024;44:3223-3230.DOI:10.21873/anticanres.17140 [doi]
8. Gao M, Liu Z, Zang H, Wu X, Yan Y, Lin H, Yuan J, Liu T, Zhou Y, Liu J. A histopathologic correlation study evaluating glymphatic function in brain tumors by multiparametric MRI. Clin Cancer Res. 2024 Nov 1;30(21):4876-4886. DOI: 10.1158/1078-0432.CCR-24-0150 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/663-03-006