Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
405-02-003 ISMRM Abstract

MRI-Derived Subtypes Identified by SuStaIn Capture Distinct Clinical, Cognitive and Disability Profiles in Multiple Sclerosis

Accepted
Loredana Storelli1, Paolo Preziosa1,2,3, Elisabetta Pagani1, Nicolo Tedone1,3, Monica Margoni1,2,4, Federica Esposito2,5, Paola Valsasina 1, Massimo Filippi1,2,3,4,6, Maria A. Rocca1,2,3
1Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy
2Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy
3Vita-Salute San Raffaele University, Milan, Italy
4Neurorehabilitation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy
5Laboratory of Human Genetics of Neurological Disorders, IRCCS San Raffaele Scientific Institute, Milan, Italy
6Neurophysiology Service, IRCCS San Raffaele Scientific Institute, Milan, Italy
Presenting Author: Paola Valsasina

Synopsis

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References

1. Lublin FD. New multiple sclerosis phenotypic classification. Eur Neurol 2014;72 Suppl 1:1-5. doi: 10.1159/000367614 [doi]
2. Eshaghi A, Young AL, Wijeratne PA, et al. Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data. Nat Commun 2021;12:2078. doi: 10.1038/s41467-021-22265-2 [doi]
3. Aksman LM, Wijeratne PA, Oxtoby NP, et al. pySuStaIn: a Python implementation of the Subtype and Stage Inference algorithm. SoftwareX 2021;16. doi: 10.1016/j.softx.2021.100811 [doi]
4. Young AL, Vogel JW, Aksman LM, et al. Ordinal SuStaIn: Subtype and Stage Inference for Clinical Scores, Visual Ratings, and Other Ordinal Data. Front Artif Intell 2021;4:613261. doi: 10.3389/frai.2021.613261 [doi]

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