Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
469-03-004 ISMRM Abstract

Impact of MRS Sequence Implementation and Fitting Models on Test-Retest Brain ¹H-MRS Quantification Accuracy

Accepted
ROCIO A ARTIGAS 1,2, Afonso Simões3, Ana Xavier3, Viola Hollestein4, Pablo Irarrazaval2,5, David G Norris4, José P Marques4
1Biomedical Imaging Center. Pontificia Universidad Católica de Chile, Santiago, Chile, Chile
2Biological and Medical Engineering Institute. Pontificia Universidad Católica de Chile, Santiago, Chile, Chile
3Departamento de Física, Faculdade de Ciências, Universidade de Lisboa, Lisbon, Portugal, Portugal
4Donders Center for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands, Netherlands
5Department of Electric Engineering. Pontificia Universidad Católica de Chile, Santiago, Chile, Chile
Presenting Author: ROCIO A ARTIGAS

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References

1. Graaf, R. A. (2019). In Vivo NMR Spectroscopy: Principles and Techniques (1.a ed.). Wiley. https://doi.org/10.1002/9781119382461 [doi]
2. Lambert, J. B., Mazzola, E. P., & Ridge, C. D. (2019). Nuclear magnetic resonance spectroscopy: An introduction to principles, applications, and experimental methods (Second edition). John Wiley & Sons.
3. McKiernan, E., Su, L., & O’Brien, J. (2023). MRS in neurodegenerative dementias, prodromal syndromes and at‐risk states: A systematic review of the literature. NMR in Biomedicine, 36(7), e4896. https://doi.org/10.1002/nbm.4896 [doi]
4. Juchem, C., & De Graaf, R. A. (2017). B0 magnetic field homogeneity and shimming for in vivo magnetic resonance spectroscopy. Analytical Biochemistry, 529, 17-29. https://doi.org/10.1016/j.ab.2016.06.003 [doi]
5. Stockmann, J. P., & Wald, L. L. (2018). In vivo B 0 field shimming methods for MRI at 7 T. NeuroImage, 168, 71-87. https://doi.org/10.1016/j.neuroimage.2017.06.013 [doi]
6. Barker, P.B. (Ed.), 2010. Clinical MR spectroscopy: techniques and applications. Cambridge University Press, Cambridge.
7. Hong, D., Van Asten, J. J. A., Rankouhi, S. R., Thielen, J.-W., & Norris, D. G. (2019). Effect of linewidth on estimation of metabolic concentration when using water lineshape spectral model fitting for single voxel proton spectroscopy at 7 T. Journal of Magnetic Resonance, 304, 53-61. https://doi.org/10.1016/j.jmr.2019.05.002 [doi]
8. Schweser, F., Robinson, S. D., De Rochefort, L., Li, W., & Bredies, K. (2017). An illustrated comparison of processing methods for phase MRI and QSM: Removal of background field contributions from sources outside the region of interest. NMR in Biomedicine, 30(4), e3604. https://doi.org/10.1002/nbm.3604 [doi]
9. Zöllner, H. J., Považan, M., Hui, S. C. N., Tapper, S., Edden, R. A. E., & Oeltzschner, G. (2021). Comparison of different linear‐combination modeling algorithms for short‐TE proton spectra. NMR in Biomedicine, 34(4), e4482. https://doi.org/10.1002/nbm.4482 [doi]
10. Miletić, S., Bazin, P.-L., Weiskopf, N., Van Der Zwaag, W., Forstmann, B. U., & Trampel, R. (2020). fMRI protocol optimization for simultaneously studying small subcortical and cortical areas at 7 T. NeuroImage, 219, 116992. https://doi.org/10.1016/j.neuroimage.2020.116992 [doi]
11. Oeltzschner, G., Zöllner, H. J., Hui, S. C. N., Mikkelsen, M., Saleh, M. G., Tapper, S., & Edden, R. A. E. (2020). Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data. Journal of Neuroscience Methods, 343, 108827. https://doi.org/10.1016/j.jneumeth.2020.108827 [doi]
12. Dou, W., Speck, O., Benner, T., Kaufmann, J., Li, M., Zhong, K., Walter, M., 2015. Automatic voxel positioning for MRS at 7 T. Magn. Reson. Mater. Phys. Biol. Med. 28, 259–270. https://doi.org/10.1007/s10334-014-0469-9 [doi]

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