Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
460-06-001 ISMRM Abstract

Functional Connectivity and Cognitive Functions: Age-Related Variations in Resting State fMRI

Primary: Brain Function and fMRI - Functional Connectivity
Secondary: Neuro - Aging
460-06-001 · Imaging the Brain’s Microenvironment: From Glymphatics to Cognition · Tuesday, 12 May, 4:55 PM–5:50 PM · Digital Posters Row A
Keywords: Ageing Resting state fMRI Functional network connectivity Healthy Age related
Accepted
Arman Deep Singh 1, Mukesh Kumar1,2, Swathi BH1, Bhargavi P1, Apurva Awasthi1, Ashwini Godbole1, Subash Khushu1
1The University of Trans-Disciplinary Health Sciences and Technology, Bengaluru, India
2Institute of Nuclear Medicine and Allied Sciences, Delhi, India
Presenting Author: Arman Deep Singh

Synopsis

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References

1. 1. Lee, J. & Kim, H.-J. Normal Aging Induces Changes in the Brain and Neurodegeneration Progress: Review of the Structural, Biochemical, Metabolic, Cellular, and Molecular Changes. Front. Aging Neurosci. 14, 931536 (2022).
2. 2. Vidal-Piñeiro, D. et al. Decreased Default Mode Network connectivity correlates with age-associated structural and cognitive changes. Front. Aging Neurosci. 6, 256 (2014).
3. 3. Ranasinghe, P. V. N. N. & Mapa, M. S. T. Functional connectivity and cognitive decline: a review of rs-fMRI, EEG, MEG, and graph theory approaches in aging and dementia. Explor. Med. 5, 797–821 (2024).
4. 4. Cera, N., Esposito, R., Cieri, F. & Tartaro, A. Altered Cingulate Cortex Functional Connectivity in Normal Aging and Mild Cognitive Impairment. Front. Neurosci. 13, 857 (2019).
5. 5. Kavroulakis, E. et al. Evidence of Age-Related Hemodynamic and Functional Connectivity Impairment: A Resting State fMRI Study. Front. Neurol. 12, (2021).
6. 6. Dongaonkar, B., Singh, A. D., Hurakadli, S. B. & Godbole, A. Glycated hemoglobin levels and geriatric depression impact cognitive status in an Indian urban elderly community. IBRO Neurosci. Rep. 19, 426–436 (2025).
7. 7. Farràs-Permanyer, L. et al. Age-related changes in resting-state functional connectivity in older adults. Neural Regen. Res. 14, 1544 (2019).
8. 8. Onoda, K., Ishihara, M. & Yamaguchi, S. Decreased Functional Connectivity by Aging Is Associated with Cognitive Decline. J. Cogn. Neurosci. 24, 2186–2198 (2012).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/460-06-001