Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
331-03-017 / 331-03-017 ISMRM Abstract

Dissociation Between Behavioral Recovery and Network Reorganization in Adolescent Rats After Mild Traumatic Brain Injury

Primary: Brain Function and fMRI - Functional Connectivity
Secondary: Neuro - Traumatic Brain Injury
331-03-017 · Clinical Applications in Psychiatry and Neurology · Monday, 11 May, 4:10 PM–5:36 PM · Roof Terrace
331-03-017 · Clinical Applications in Psychiatry and Neurology · Monday, 11 May, 4:10 PM–5:36 PM · Roof Terrace
Keywords: Animals fMRI (resting state) Adolescents Functional Connectivity Mild Traumatic Brain Injury
Accepted
Yun-Yun Liu 1, Pin-Hui Kuo1, Ying-Wei Sung1, Huai-An Kuo2, Chia-Feng Lu1, Yu-Chieh Jill Kao1
1Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan
2School of Medical Sciences, University of Sydney, Camperdown, Australia
Presenting Author: Yun-Yun Liu

Synopsis

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References

1. Newsome, M.R., et al., Functional Connectivity Is Altered in Concussed Adolescent Athletes Despite Medical Clearance to Return to Play: A Preliminary Report. Front Neurol, 2016. 7: p. 116. https://doi.org/10.3389/fneur.2016.00116 [doi]
2. Crasta, J.E., et al., Rethinking recovery in adolescent concussions: Network-level functional connectivity alterations associated with motor deficits. Hum Brain Mapp, 2023. 44(8): p. 3271-3282. https://doi.org/10.1002/hbm.26280 [doi]
3. Kao, Y.J., et al., Behavioral and Structural Effects of Single and Repeat Closed-Head Injury. AJNR Am J Neuroradiol, 2019. 40(4): p. 601-608. https://doi.org/10.3174/ajnr.A6014 [doi]
4. Sung, Y.-W., et al., Resting-State Functional Magnetic Resonance Imaging in the Adolescent Rats under the Combination of Isoflurane and Dexmedetomidine. Brain Research Bulletin, 2025: p. 111600. https://doi.org/10.1016/j.brainresbull.2025.111600 [doi]
5. Fan, F., et al., Development of the default-mode network during childhood and adolescence: A longitudinal resting-state fMRI study. Neuroimage, 2021. 226: p. 117581. https://doi.org/10.1016/j.neuroimage.2020.117581 [doi]
6. Rebello, K., et al., Default Mode Network Maturation and Environmental Adversities During Childhood. Chronic Stress (Thousand Oaks), 2018. 2: p. 2470547018808295. https://doi.org/10.1177/2470547018808295 [doi]
7. Morelli, N., et al., Resting state functional connectivity responses post-mild traumatic brain injury: a systematic review. Brain Inj, 2021. 35(11): p. 1326-1337. https://doi.org/10.1080/02699052.2021.1972339 [doi]
8. Sun, C.C., et al., Modified constraint-induced movement therapy enhances cortical plasticity in a rat model of traumatic brain injury: a resting-state functional MRI study. Neural Regen Res, 2023. 18(2): p. 410-415. https://doi.org/10.4103/1673-5374.344832 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/331-03-017