Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
652-01-004 / 652-01-004 ISMRM Abstract

Interpretable Machine Learning Model for predicting Neoadjuvant Chemotherapy Response in Advanced Olfactory Neuroblastoma

Primary: Neuro - Tumors
Secondary: Analysis Methods - Classification and Prediction
652-01-004 · Prognostication and Predictive Value of MR Biomarkers · Thursday, 14 May, 8:30 AM–10:06 AM · Power Pitch Theatre 2
652-01-004 · Prognostication and Predictive Value of MR Biomarkers · Thursday, 14 May, 8:30 AM–10:06 AM · Power Pitch Theatre 2
Keywords: Diagnosis/Prediction Machine learning Neoadjuvant Chemotherapy Olfactory Neuroblastoma
Accepted
Shanbin Sun 1, Xiwen Wang1, yongchao wu1, Dandan Zheng2, Jing Peng2, Zhaohui Liu1
1Beijing Tongren Hospital, Capital Medical University, Beijing, China
2Clinical & Technique Support, Clinical and Technical Support, Philips Healthcare (Beijing), Beijing, China
Presenting Author: Shanbin Sun

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A. Update on olfactory neuroblastoma. Virchows Arch. 2024 Apr;484(4):567-585. doi: 10.1007/s00428-024-03758-z. Epub 2024 Feb 22. PMID: 38386106. [doi] [pmid]
2. Hirunpat P, Panyaping T, Hirunpat S. Olfactory Neuroblastoma Is Not Always Located at the Roof of the Nasal Cavity. J Belg Soc Radiol. 2024 Apr 12;108(1):39. doi: 10.5334/jbsr.3562. PMID: 38826683; PMCID: PMC11141505. [doi] [pmid]
3. Singh L, Ranjan R, Madan R, Arava SK, Deepak RK, Singh MK. Microvessel density and Ki-67 labeling index in esthesioneuroblastoma: is there a prognostic role? Ann Diagn Pathol. 2015 Dec;19(6):391-6. doi: 10.1016/j.anndiagpath.2015.06.008. Epub 2015 Jul 18. PMID: 26343569. [doi] [pmid]
4. Abdelmeguid AS. Olfactory Neuroblastoma. Curr Oncol Rep. 2018 Feb 7;20(1):7. doi: 10.1007/s11912-018-0661-6. PMID: 29411144. [doi] [pmid]
5. Rao KR, Upadhya IB. A Review on Esthesioneuroblastoma. Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1584-1590. doi: 10.1007/s12070-021-02726-2. Epub 2021 Jul 9. PMID: 36452592; PMCID: PMC9702120. [doi] [pmid]
6. Bartel R, Gonzalez-Compta X, Cisa E, Cruellas F, Torres A, Rovira A, Manos M. Importance of neoadjuvant chemotherapy in olfactory neuroblastoma treatment: Series report and literature review. Acta Otorrinolaringol Esp (Engl Ed). 2018 Jul-Aug;69(4):208-213. English, Spanish. doi: 10.1016/j.otorri.2017.07.001. Epub 2017 Oct 20. PMID: 29061289. [doi] [pmid]
7. De Bonnecaze G, Lepage B, Rimmer J, Al Hawat A, Vairel B, Serrano E, Chaput B, Vergez S. Long-term carcinologic results of advanced esthesioneuroblastoma: a systematic review. Eur Arch Otorhinolaryngol. 2016 Jan;273(1):21-6. doi: 10.1007/s00405-014-3320-z. Epub 2014 Oct 17. PMID: 25323151. [doi] [pmid]
8. Wang Y, Zhang S, Yu W, Wang Y, Yan F, Yang B. The role of ADC value and Ki-67 index in predicting the response to neoadjuvant chemotherapy in advanced stages of olfactory neuroblastoma. Br J Radiol. 2022 Dec 1;95(1140):20220367. doi: 10.1259/bjr.20220367. Epub 2022 Nov 15. PMID: 36240450; PMCID: PMC9733604. [doi] [pmid]
9. Crivelli P, Ledda RE, Parascandolo N, Fara A, Soro D, Conti M. A New Challenge for Radiologists: Radiomics in Breast Cancer. Biomed Res Int. 2018 Oct 8;2018:6120703. doi: 10.1155/2018/6120703. PMID: 30402486; PMCID: PMC6196984. [doi] [pmid]
10. Cho SW, Keam B, Lee KW, Kim JW, Han DH, Kim HJ, Kim JW, Kim DY, Rhee CS, Bae YJ, Kim JH, Eom KY, Wu HG, Kim YH, Kim CY, Paek SH, Kim H, Won TB. Role of induction chemotherapy in advanced-stage olfactory neuroblastoma. Int Forum Allergy Rhinol. 2024 Dec;14(12):1882-1891. doi: 10.1002/alr.23428. Epub 2024 Aug 20. PMID: 39162101. [doi] [pmid]
11. Patil VM, Joshi A, Noronha V, Sharma V, Zanwar S, Dhumal S, Kane S, Pai P, D'Cruz A, Chaturvedi P, Bhattacharjee A, Prabhash K. Neoadjuvant Chemotherapy in Locally Advanced and Borderline Resectable Nonsquamous Sinonasal Tumors (Esthesioneuroblastoma and Sinonasal Tumor with Neuroendocrine Differentiation). Int J Surg Oncol. 2016;2016:6923730. doi: 10.1155/2016/6923730. Epub 2016 Feb 3. PMID: 26955484; PMCID: PMC4756189. [doi] [pmid]
12. Huang EP, O'Connor JPB, McShane LM, Giger ML, Lambin P, Kinahan PE, Siegel EL, Shankar LK. Criteria for the translation of radiomics into clinically useful tests. Nat Rev Clin Oncol. 2023 Feb;20(2):69-82. doi: 10.1038/s41571-022-00707-0. Epub 2022 Nov 28. PMID: 36443594; PMCID: PMC9707172. [doi] [pmid]
13. Zhu W, Xu Y, Zhu H, Qiu B, Zhan M, Wang H. Multi-parametric MRI radiomics for predicting response to neoadjuvant therapy in patients with locally advanced rectal cancer. Jpn J Radiol. 2024 Dec;42(12):1448-1457. doi: 10.1007/s11604-024-01630-3. Epub 2024 Jul 29. PMID: 39073521. [doi] [pmid]
14. Hu T, Gong J, Sun Y, Li M, Cai C, Li X, Cui Y, Zhang X, Tong T. Magnetic resonance imaging-based radiomics analysis for prediction of treatment response to neoadjuvant chemoradiotherapy and clinical outcome in patients with locally advanced rectal cancer: A large multicentric and validated study. MedComm (2020). 2024 Jun 20;5(7):e609. doi: 10.1002/mco2.609. PMID: 38911065; PMCID: PMC11190348. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/652-01-004