401-04-007 ISMRM Abstract

23Na-MRI and 1H-MRI to quantify the magnitude and time course of muscle disruption after high-load eccentric contractions

Primary: Contrast Mechanisms - Non-Proton

Secondary: Musculoskeletal - Muscle

401-04-007 · Metabolism · Tuesday, 12 May, 4:00 PM–5:50 PM · Hall 1A

Keywords: Metabolism MSK 23Na MRI 3.0T

Accepted

Ben Prestwich ¹, Charles J Steward², Theodora Slater¹, Abhishek Sheth², Joanne Mallinson², Paul L Greenhaff^1,2,3, Susan Francis^1,3

¹Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom

²The David Greenfield Human Physiology Laboratory, School of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom

³NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom

Presenting Author: Ben Prestwich

Synopsis

Motivation:

Goals:

Approach:

Results:

Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

References

1. Cleak, M. J., & Eston, R. G. (1992). Muscle soreness, swelling, stiffness and strength loss after intense eccentric exercise. British journal of sports medicine, 26(4), 267-272. DOI: https://doi.org/10.1136/bjsm.26.4.267 [doi]

2. Hoger, S. A., Gast, L. V., Marty, B., Hotfiel, T., Bickelhaupt, S., Uder, M., ... & Nagel, A. M. (2023). Sodium and quantitative hydrogen parameter changes in muscle tissue after eccentric exercise and in delayed‐onset muscle soreness assessed with magnetic resonance imaging. NMR in Biomedicine, 36(2), e4840. DOI: https://doi.org/10.1002/nbm.4840 [doi]

3. Prestwich, B & Francis, S. T. , Comparison of short and long TR Gradient Recalled Echo (GRE) measure of total sodium concentration mapping in the calf. Proc Intl Soc Mag Reson Med; 2023, Toronto, 4729 DOI: https://doi.org/10.58530/2023/4729 [doi]

4. Prestwich, B & Francis, S. T. Design of a dynamic Sodium (23Na) phantom to evaluate NORDIC on changes in tissue sodium concentration. Proc Intl Soc Mag Reson Med; 2025, Honolulu, 0928. DOI: https://doi.org/10.58530/2024/0928 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/401-04-007