Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
551-02-014 / 551-02-014 ISMRM Abstract

Blood-brain barrier leakage may be associated with cognitive decline in chronic kidney disease patients

Primary: Diffusion - IVIM
Secondary: Neuro - Other Neurodegeneration
551-02-014 · MRI of Renal Function · Wednesday, 13 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
551-02-014 · MRI of Renal Function · Wednesday, 13 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
Keywords: FEXI Blood-brain barrier Chronic Kidney Disease Cognitive decline Kidney-brain axis
Accepted
Wenbo Yang 1, Lijun Song1, Yanfang Tan2, Boyan Xu3, Min Li2, Weikang Guo1, Hao Wang1, Zhenchang Wang1
1Beijing Friendship Hospital, Capital Medical University, beijing, China
2Clinical Epidemiology and EBM Unit, Beijing Friendship Hospital, Capital Medical University, Beijing, China
3MR Research, GE Healthcare, Beijing, China
Presenting Author: Wenbo Yang

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References

1. Drew DA, Weiner DE, Sarnak MJ. Cognitive Impairment in CKD: Pathophysiology, Management, and Prevention. Am J Kidney Dis. Dec 2019;74(6):782-790. doi:10.1053/j.ajkd.2019.05.017 [doi]
2. Daneman R, Prat A. The blood-brain barrier. Cold Spring Harb Perspect Biol. Jan 5 2015;7(1):a020412. doi:10.1101/cshperspect.a020412 [doi]
3. Hergert DC, Gaasedelen O, Ryman SG, Prestopnik J, Caprihan A, Rosenberg GA. Blood-Brain Barrier Permeability Is Associated With Cognitive Functioning in Normal Aging and Neurodegenerative Diseases. J Am Heart Assoc. Jul 16 2024;13(14):e034225. doi:10.1161/JAHA.124.034225 [doi]
4. Bai R, Li Z, Sun C, Hsu YC, Liang H, Basser P. Feasibility of filter-exchange imaging (FEXI) in measuring different exchange processes in human brain. Neuroimage. Oct 1 2020;219:117039. doi:10.1016/j.neuroimage.2020.117039 [doi]
5. Henschel L, Conjeti S, Estrada S, Diers K, Fischl B, Reuter M. FastSurfer - A fast and accurate deep learning based neuroimaging pipeline. Neuroimage. Oct 1 2020;219:117012. doi:10.1016/j.neuroimage.2020.117012 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/551-02-014