Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
364-06-007 ISMRM Abstract

A Study on the Predictive Value of DTI and ASL Histogram Features for MGMT Status and Prognosis in Glioblastoma

Primary: Neuro - Head & Neck/ENT
Secondary: Diffusion - DWI/DTI/DKI
364-06-007 · Classification in Diffusion MRI II · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row E
Keywords: Diffusion Tensor Imaging Glioblastoma Arterial spin labeling Prognosis O6-methylguanine-DNA methyltransferase
Accepted
Fengwei Yu 1, Hailong Jiang2, Pinzhen Chen, Jing Yang, Ruishan Liu, Jianping Yang, Jiafei Chen, Wei Chen1
1Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China
2Army Medical University (Third Military Medical University), Chongqing, China
Presenting Author: Fengwei Yu

Synopsis

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References

1. [1] HORBINSKI C, BERGER T, PACKER R J, WEN P Y. Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours [J]. Nat Rev Neurol, 2022, 18(9): 515-29. DOI:10.1038/s41582-022-00679-w. [doi]
2. [2] HORBINSKI C, NABORS L B, PORTNOW J, et al. NCCN Guidelines® Insights: Central Nervous System Cancers, Version 2.2022 [J]. J Natl Compr Canc Netw, 2023, 21(1): 12-20. DOI:10.6004/jnccn.2023.0002. [doi]
3. [3] HEGI M E, DISERENS A C, GORLIA T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma [J]. N Engl J Med, 2005, 352(10): 997-1003. DOI:10.1056/NEJMoa043331. [doi]
4. [4] STUPP R, MASON W P, VAN DEN BENT M J, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma [J]. N Engl J Med, 2005, 352(10): 987-96. DOI:10.1056/NEJMoa043330. [doi]
5. [5] WANG N, XIE S Y, LIU H M, et al. Arterial Spin Labeling for Glioma Grade Discrimination: Correlations with IDH1 Genotype and 1p/19q Status [J]. Transl Oncol, 2019, 12(5): 749-56. DOI:10.1016/j.tranon.2019.02.013. [doi]
6. [6] DUY HUNG N, MINH DUC N, VAN ANH N T, et al. Diagnostic performance of diffusion tensor imaging for preo- perative glioma grading [J]. Clin Ter, 2021, 172(4): 315-21. DOI:10.7417/ct.2021.2335. [doi]

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http://echo.ismrm.org/p/ISMRM2026/364-06-007