Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
570-10-242 ISMRM Abstract

Research on brain functional connectivity and temporal variability in patients with primary Sjogren's syndrome

Primary: Brain Function and fMRI - Functional Connectivity
Secondary: Brain Function and fMRI - fMRI Analysis
570-10-242 · Brain Function Application on Paper · Wednesday, 13 May, 4:55 PM–5:50 PM · Traditional Posters | Exhibition Hall
Keywords: Functional Connectivity Temporal Variability Primary Sjogrens syndrome Degree centrality Voxel-mirrored homotopic connectivity
Accepted
Chunfeng Hu 1, Luoyu Wang2,3, Chengcheng Gao1, Jiao Huang4, Xiaofang Zhang4, Zhongxiang Ding4,5, Xiuhong Ge4, Peiying Wei1
1Department of Radiology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, China
2Shanghai Tech University, Shanghai, China
3School of Biomedical Engineering, ShanghaiTech University, Shanghai, China
4Hangzhou First People's Hospital, Hangzhou, China
5Department of Radiology, Affiliated Hangzhou First People's Hospital,Westlake University School of Medicine,Hangzhou,China.hangzhoudzx73@126.com., China
Presenting Author: Chunfeng Hu

Synopsis

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References

1. Chatzis L, Vlachoyiannopoulos PG, Tzioufas AG, Goules AV. New frontiers in precision medicine for Sjogren's syndrome. Expert Rev Clin Immunol. 2021;17(2):127-141. doi:10.1080/1744666X.2021.1879641 [doi]
2. Fan W, Par-Young J, Li K, et al. Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome. Clin Rheumatol. 2023;42(2):443-451. doi:10.1007/s10067-022-06448-w [doi]
3. Fauchais AL, Magy L, Vidal E. Central and peripheral neurological complications of primary Sjögren's syndrome. Presse Med. 2012;41(9 Pt 2):e485-e493. doi:10.1016/j.lpm.2012.06.002 [doi]
4. Shen Ren, Junhua Li, Taya F, deSouza J, Thakor NV, Bezerianos A. Dynamic Functional Segregation and Integration in Human Brain Network During Complex Tasks. IEEE Trans Neural Syst Rehabil Eng. 2017;25(6):547-556. doi:10.1109/TNSRE.2016.2597961 [doi]
5. Zhang XD, Zhao LR, Zhou JM, et al. Altered hippocampal functional connectivity in primary Sjögren syndrome: a resting-state fMRI study. Lupus. 2020;29(5):446-454. doi:10.1177/0961203320908936 [doi]
6. Pan P, Ou Y, Su Q, et al. Voxel-based global-brain functional connectivity alterations in first-episode drug-naive patients with somatization disorder. J Affect Disord. 2019;254:82-89. doi:10.1016/j.jad.2019.04.099 [doi]
7. Hu H, Wang L, Abdul S, et al. Frequency-dependent alterations in functional connectivity in patients with Alzheimer's Disease spectrum disorders. Front Aging Neurosci. 2024;16:1375836. Published 2024 Mar 28. doi:10.3389/fnagi.2024.1375836 [doi]
8. Zuo XN, Ehmke R, Mennes M, et al. Network centrality in the human functional connectome. Cereb Cortex. 2012;22(8):1862-1875. doi:10.1093/cercor/bhr269 [doi]
9. Zuo XN, Kelly C, Di Martino A, et al. Growing together and growing apart: regional and sex differences in the lifespan developmental trajectories of functional homotopy. J Neurosci. 2010;30(45):15034-15043. doi:10.1523/JNEUROSCI.2612-10.2010 [doi]
10. Hu H, Wang L, Abdul S, et al. Frequency-dependent alterations in functional connectivity in patients with Alzheimer's Disease spectrum disorders. Front Aging Neurosci. 2024;16:1375836. Published 2024 Mar 28. doi:10.3389/fnagi.2024.1375836 [doi]
11. Liu G, Lu W, Qiu J, Shi L. Identifying individuals with attention-deficit/hyperactivity disorder based on multisite resting-state functional magnetic resonance imaging: A radiomics analysis. Hum Brain Mapp. 2023;44(8):3433-3445. doi:10.1002/hbm.26290 [doi]
12. Shi D, Zhang H, Wang G, et al. Neuroimaging biomarkers for detecting schizophrenia: A resting-state functional MRI-based radiomics analysis. Heliyon. 2022;8(12):e12276. Published 2022 Dec 10. doi:10.1016/j.heliyon.2022.e12276 [doi]
13. Allen EA, Damaraju E, Plis SM, Erhardt EB, Eichele T, Calhoun VD. Tracking whole-brain connectivity dynamics in the resting state. Cereb Cortex. 2014;24(3):663-676. doi:10.1093/cercor/bhs352 [doi]
14. Hu C, Wang L, Huang J, et al. Regional brain function study in patients with primary Sjögren's syndrome. Arthritis Res Ther. 2025;27(1):93. Published 2025 Apr 23. doi:10.1186/s13075-025-03554-3 [doi]
15. Hu C, Wang L, Ge X, et al. Frequency-dependent and temporal variability of low-frequency fluctuations in patients with primary Sjögren's syndrome. Lupus Sci Med. 2025;12(2):e001655. Published 2025 Sep 16. doi:10.1136/lupus-2025-001655 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/570-10-242