Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
360-05-003 ISMRM Abstract

4D Flow MRI–Derived Metrics to Characterize Pulmonary Hypertension Phenotypes

Primary: Cardiovascular - Flow
Secondary: Cardiovascular - Heart Failure
360-05-003 · Acquisition, Reconstruction, and Analysis · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row A
Keywords: 4D flow MRI Hemodynamics Heart failure with preserved ejection fraction Pulmonary hypertension
Accepted
Timothy W Houston 1, Farhan Raza2, Ethan Johnson3, Michael Markl3,4, Oliver Wieben5
1Medical Physics, University of Wisconsin - Madison, Madison, United States of America
2Department of Medicine, University of Wisconsin - Madison, Madison, United States of America
3Radiology, Northwestern University, Chicago, United States of America
4Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States of America
5Medical Physics and Radiology, University of Wisconsin - Madison, Madison, United States of America
Presenting Author: Timothy W Houston

Synopsis

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References

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2. Rosenkranz S, Gibbs JS, Wachter R, De Marco T, Vonk-Noordegraaf A, Vachiéry JL. Left ventricular heart failure and pulmonary hypertension. Eur Heart J. 2016 Mar 21;37(12):942-54. doi: 10.1093/eurheartj/ehv512. Epub 2015 Oct 27. PMID: 26508169; PMCID: PMC4800173. [doi] [pmid]
3. Al-Omary MS, Sugito S, Boyle AJ, Sverdlov AL, Collins NJ. Pulmonary Hypertension Due to Left Heart Disease: Diagnosis, Pathophysiology, and Therapy. Hypertension. 2020 Jun;75(6):1397-1408. doi: 10.1161/HYPERTENSIONAHA.119.14330. Epub 2020 Apr 27. PMID: 32336230. [doi] [pmid]
4. Levine AR, Simon MA, Gladwin MT. Pulmonary vascular disease in the setting of heart failure with preserved ejection fraction. Trends Cardiovasc Med. 2019 May;29(4):207-217. doi: 10.1016/j.tcm.2018.08.005. Epub 2018 Aug 17. PMID: 30177249; PMCID: PMC6378124. [doi] [pmid]
5. Bissell MM, Raimondi F, Ait Ali L, et al. 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update. J Cardiovasc Magn Reson. 2023 Jul 20;25(1):40. doi: 10.1186/s12968-023-00942-z. PMID: 37474977; PMCID: PMC10357639. [doi] [pmid]
6. Markl M, Frydrychowicz A, Kozerke S, Hope M, Wieben O. 4D flow MRI. J Magn Reson Imaging. 2012 Nov;36(5):1015-36. doi: 10.1002/jmri.23632. PMID: 23090914. [doi] [pmid]
7. Shafeghat M, Houston TW, et al. Preliminary findings from 4D-flow MRI on left heart hemodynamics in Chronic Obstructive Pulmonary Disease: The SPIROMICS Heart Failure Study. Novel Techniques in CMR. Abstract #3666. ISMRM, 14 May 2025.
8. Ota H, Kamada H, Higuchi S, Takase K. Clinical Application of 4D Flow MR Imaging to Pulmonary Hypertension. Magn Reson Med Sci. 2022 Mar 1;21(2):309-318. doi: 10.2463/mrms.rev.2021-0111. Epub 2022 Feb 19. PMID: 35185084; PMCID: PMC9680544. [doi] [pmid]
9. Borhani A, Porter KK, Umair M, el al. Quantifying 4D flow cardiovascular magnetic resonance vortices in patients with pulmonary hypertension: A pilot study. Pulm Circ. 2023 Oct 18;13(4):e12298. doi: 10.1002/pul2.12298. PMID: 37859803; PMCID: PMC10583650. [doi] [pmid]
10. Johnson EMI, Berhane H, Weiss E, et al. A Fully Automated Analysis Pipeline for 4D Flow MRI in the Aorta. Bioengineering. 2025; 12(8):807. https://doi.org/10.3390/bioengineering12080807 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/360-05-003