552-02-011 / 552-02-011 ISMRM Abstract

Improving knee articular cartilage T2 repeatability with optimized open-source Multi-Spin Echo sequences

Primary: Acquisition & Reconstruction - Quantitative Imaging: spine, MSK, others

Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI

552-02-011 · Quantitative Imaging: Relaxometry, Multiparametric, MR Fingerprinting, and Synthetic MRI · Wednesday, 13 May, 1:40 PM–3:16 PM · Power Pitch Theatre 2

Keywords: Optimization Repeatability T2 mapping Pulseq Articular cartilage

Accepted

Tiago Timoteo Fernandes ¹, Andreia S Gaspar¹, Amir Esrafilian^2,3, Jochen Schmidt^4,5, Jose M Coelho^6,7, Vasco Mascarenhas⁸, Sairam Geethanath⁹, Rita G Nunes¹

¹Institute for Systems and Robotics – Lisboa and Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal

²Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

³Stanford University, Stanford, United States of America

⁴Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

⁵Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

⁶Clínica de Imagiologia Diagnóstica e de Intervenção, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal

⁷Radiology Department, Escola Superior de Saúde / Instituto Politécnico do Porto, Porto, Portugal

⁸Hospital da Luz Learning Health, Luz Saúde, Lisbon, Portugal

⁹Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, United States of America

Presenting Author: Tiago Timoteo Fernandes

Synopsis

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References

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2. Joseph GB, Baum T, Alizai H, Carballido-Gamio J, Nardo L, Virayavanich W, et al. Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years--data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2012;20: 727–735. PMID: 22503812 PMCID: PMC3595156 DOI: 10.1016/j.joca.2012.04.003 [doi] [pmid]

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8. Layton KJ, Kroboth S, Jia F, Littin S, Yu H, Leupold J, et al. Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magn Reson Med. 2017;77: 1544–1552. PMID: 27271292 DOI: 10.1002/mrm.26235 [doi] [pmid]

9. Fernandes TT, Gaspar AS, Schmidt J, Alfaite A, Scheibe P, Coelho JM, Mascarenhas V, Geethanath S, Nunes RG. ISMRM. Open-source Multi-Spin Echo T2 Mapping Optimized for Knee Articular Cartilage. [cited 29 Oct 2025]. Available: https://archive.ismrm.org/2025/2592_6ffhKsQ4p.html

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13. Zhang X, de Moura HL, Monga A, Zibetti MVW, Kijowski R, Regatte RR. Repeatability of Quantitative Knee Cartilage T, T, and T Mapping With 3D-MRI Fingerprinting. J Magn Reson Imaging. 2024;60: 688–699. PMID: 37885320 PMCID: PMC11045656 DOI: 10.1002/jmri.29068 [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/552-02-011