Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
364-01-004 ISMRM Abstract

Altered Neurovascular Coupling in Relation to Spatial Navigation in Subjective Cognitive Decline: Insights from 5.0Tesla MRI

Primary: Neuro - Alzheimer's Disease
Secondary: Brain Function and fMRI - fMRI Analysis
364-01-004 · fMRI: Analyses · Monday, 11 May, 8:20 AM–9:15 AM · Digital Posters Row E
Accepted
Futao Chen 1, Lixian Zou2,3, Jiaming Lu1,4,5, Qian Chen1, Yichen Wang6, Bing Zhang1,4
1Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
2Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
3Key Laboratory for Magnetic Resonance and Multimodality Imaging of Guangdong Province, Shenzhen, China
4Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China
5Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
6Collaborative Innovation Department, United Imaging Health Care Group Co., Shanghai, China
Presenting Author: Futao Chen

Synopsis

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References

1. Jessen F, Amariglio R E, Buckley R F, et al. The characterisation of subjective cognitive decline [J]. The Lancet Neurology, 2020, 19(3): 271-8. doi: 10.1016/S1474-4422(19)30368-0 [doi]
2. Levine T F, Allison S L, Stojanovic M, et al. Spatial navigation ability predicts progression of dementia symptomatology [J]. Alzheimers Dement, 2020, 16(3): 491-500. doi: 10.1002/alz.12031 [doi]
3. Li J, Zeng Q, Luo X, et al. Decoupling of Regional Cerebral Blood Flow and Brain Function Along the Alzheimer’s Disease Continuum [J]. Journal of Alzheimer's Disease, 2023, 95(1): 287-98. doi: 10.3233/JAD-230503 [doi]
4. Yan C G, Wang X D, Zuo X N, et al. DPABI: Data Processing & Analysis for (Resting-State) Brain Imaging [J]. Neuroinformatics, 2016, 14(3): 339-51. doi: 10.1007/s12021-016-9299-4 [doi]
5. Csiszar A, Tarantini S, Fülöp G A, et al. Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer’s disease [J]. GeroScience, 2017, 39(4): 359-72. doi: 10.1007/s11357-017-9991-9 [doi]
6. Chow B W, Nuñez V, Kaplan L, et al. Caveolae in CNS arterioles mediate neurovascular coupling [J]. Nature, 2020, 579(7797): 106-10. doi: 10.1038/s41586-020-2026-1 [doi]

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http://echo.ismrm.org/p/ISMRM2026/364-01-004