Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
564-04-010 ISMRM Abstract

Subcortical volume alterations in first-episode, drug-naïve adolescents with major depressive disorder

Primary: Neuro - Psychiatric Disorders
Secondary: Neuro - Gray Matter
564-04-010 · Imaging Depression · Wednesday, 13 May, 2:35 PM–3:30 PM · Digital Posters Row E
Keywords: Adolescents Subcortical structure Major depressive disorder Structural MRI First-episode drug-naive
Accepted
Baoshuai Zhang 1,2, Baolin Wu1,2, Qiyong Gong1,2,3
1Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, China
2Department of Radiology, Huaxi MR Research Center (HMRRC), Institute of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China
3Xiamen Key Lab of Psychoradiology and Neuromodulation, Department of Radiology, West China Xiamen Hospital of Sichuan University, Xiamen, Fujian, China
Presenting Author: Baoshuai Zhang

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References

1. Thapar A, Eyre O, Patel V, Brent D: Depression in young people. Lancet (London, England) 2022;400:617-631.
2. Lenroot RK, Giedd JN: Brain development in children and adolescents: insights from anatomical magnetic resonance imaging. Neuroscience and biobehavioral reviews 2006;30:718-729.
3. Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos A, Paus T, Evans AC, Rapoport JL: Brain development during childhood and adolescence: a longitudinal MRI study. Nature neuroscience 1999;2:861-863.
4. Giedd, J. N., & Rapoport, J. L. (2010). Structural MRI of pediatric brain development: what have we learned and where are we going? Neuron, *67*(5), 728–734.
5. Schmaal, L., Veltman, D. J., van Erp, T. G., et al. (2016). Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group.
6. Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009). Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nature Reviews Neuroscience, *10*(6), 434–445.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/564-04-010