Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
460-05-012 ISMRM Abstract

7T MRI reveals altered glymphatic function in Cushing’s Disease: a study of enlarged perivascular space

Primary: Neuro - Neurofluids
Secondary: Analysis Methods - Segmentation and Detection
460-05-012 · When Brain Clearance Fails: Glymphatic Dysfunction Across Disorders · Tuesday, 12 May, 4:00 PM–4:55 PM · Digital Posters Row A
Keywords: Neurofluids 7T Perivascular spaces Glymphatic system
Accepted
Yuan Li1, Yanglei Wu 2, Zeyu Liu3, Xinying Huang4, Feng Feng3
1MR Research Collaboration, Siemens Healthineers Ltd., Beijing, China
2Department of Radiology, Charité – Universitätsmedizin Berlin, Berlin, Germany
3Peking Union Medical College Hospital, Beijing, China
4department of radiology, Peking Union Medical College Hospital, Beijing, China
Presenting Author: Yanglei Wu

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References

1. Mark S. New York: Thieme Medical Publishers. 7 2010. Greenberg. Handbook of Neurosurgery.
2. Ross EJ, Linch DC. Cushing’s syndrome: killing disease: discriminatory value of signs and symptoms aiding early diagnosis. Lancet. 1982;2:646–649. doi:10.1016/s0140-6736(82)92749-0. [doi]
3. Yu L, Hu X, Li H, Zhao Y. Perivascular Spaces, Glymphatic System and MR. Front Neurol. 2022 May 3;13:844938. doi: 10.3389/fneur.2022.844938. [doi]
4. Herrler J, Liebig P, Gumbrecht R, Ritter D, Schmitter S, Maier A, Schmidt M, Uder M, Doerfler A, Nagel AM. Fast online-customized (FOCUS) parallel transmission pulses: A combination of universal pulses and individual optimization. Magn Reson Med. 2021 Jun;85(6):3140-3153. DOI: 10.1002/mrm.28643 [doi]
5. Ballerini, L., Lovreglio, R., Valdés Hernández, M.d.C. et al. Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering. Sci Rep 8, 2132 (2018). doi:10.1038/s41598-018-19781-5 [doi]
6. Sepehrband, F., Barisano, G., Sheikh-Bahaei, N. et al. Image processing approaches to enhance perivascular space visibility and quantification using MRI. Sci Rep 9, 12351 (2019). doi:10.1038/s41598-019-48910-x [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/460-05-012