Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
460-01-006 ISMRM Abstract

Dual-acquisition calibrated fMRI improves CMRO₂ and CBF/BOLD coupling in resting state compared to conventional dual-echo ASL

Primary: Brain Function and fMRI - Functional Connectivity
Secondary: Brain Function and fMRI - fMRI Acquisition
460-01-006 · Brain Physiology and Pain · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row A
Keywords: Functional Connectivity Calibrated fMRI CMRO2 CBF-BOLD coupling
Accepted
Ines Chavarria Marques1, Marta Vidorreta2, Maria Fernandez-Seara3,4,5,6,7,8, César Caballero-Gaudes 1,9
1Basque Center on Cognition, Brain and Language, San Sebastian - Donostia, Spain
2Siemens Healthcare, Madrid, Spain
3Clinica Universidad de Navarra, Pamplona, Spain
4Navarra Institute for Health Research (IdiSNa), Pamplona, Spain, Spain
5Department of Radiology, Clínica Universidad de Navarra, Spain, Spain
6Navarra Institute for Health Research (IdiSNa), Pamplona, Spain
7Department of Radiology, Clinica Universidad de Navarra, Pamplona, Spain
8Radiology, Clinica Universidad de Navarra, Pamplona, Spain
9Ikerbasque, Basque Foundation for Science, Bilbao, Spain
Presenting Author: César Caballero-Gaudes

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References

1. Zhang, K., Huang, D., & Shah, N. J. (2018). Comparison of Resting-State Brain Activation Detected by BOLD, Blood Volume and Blood Flow. Frontiers in Human Neuroscience, 12, 443. https://doi.org/10.3389/fnhum.2018.00443 [doi]
2. Dipasquale, O., Cohen, A., Martins, D. et al. Molecular-enriched functional connectivity in the human brain using multiband multi-echo simultaneous ASL/BOLD fMRI. Sci Rep 13, 11751 (2023). https://doi.org/10.1038/s41598-023-38573-0 [doi]
3. Fernández-Seara, M. A., Rodgers, Z. B., Englund, E. K., & Wehrli, F. W. (2016). Calibrated bold fMRI with an optimized ASL-BOLD dual-acquisition sequence. NeuroImage, 142, 474-482. https://doi.org/10.1016/j.neuroimage.2016.08.007 [doi]
4. Schmithorst, V. J., Hernandez-Garcia, L., Vannest, J., Rajagopal, A., Lee, G., & Holland, S. K. (2014). Optimized simultaneous ASL and BOLD functional imaging of the whole brain. Journal of Magnetic Resonance Imaging, 39(5), 1104-1117. https://doi.org/10.1002/jmri.24273 [doi]
5. Kundu, P., Inati, S. J., Evans, J. W., Luh, W. M., & Bandettini, P. A. (2012). Differentiating BOLD and non-BOLD signals in fMRI time series using multi-echo EPI. Neuroimage, 60(3), 1759-1770.
6. Kundu, P., Voon, V., Balchandani, P., Lombardo, M. V., Poser, B. A., & Bandettini, P. A. (2017). Multi-echo fMRI: A review of applications in fMRI denoising and analysis of BOLD signals. Neuroimage, 154, 59-80.
7. DuPre, E., Salo, T., Ahmed, Z., Bandettini, P. A., Bottenhorn, K. L., Caballero-Gaudes, C., ... & Handwerker, D. A. (2021). TE-dependent analysis of multi-echo fMRI with* tedana. Journal of Open Source Software, 6(66), 3669.
8. Halani, S., Kwinta, J. B., Golestani, A. M., Khatamian, Y. B., & Chen, J. J. (2015). Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive reactivity. NeuroImage, 110, 110-123. https://doi.org/10.1016/j.neuroimage.2015.01.050 [doi]
9. Behzadi, Y., Restom, K., Liau, J., & Liu, T. T. (2007). A component based noise correction method (CompCor) for BOLD and perfusion based fMRI. NeuroImage, 37(1), 90–101. https://doi.org/10.1016/j.neuroimage.2007.04.042 [doi]
10. Cohen, A. D., Moia, S., Pike, G. B., Caballero-Gaudes, C., & Wang, Y. (2025). Resting state BOLD-perfusion coupling patterns using multiband multi-echo pseudo-continuous arterial spin label imaging. Scientific Reports, 15(1), 2108. https://doi.org/10.1038/s41598-024-81305-1 [doi]
11. Dosenbach, N. U., Nardos, B., Cohen, A. L., Fair, D. A., Power, J. D., Church, J. A., Nelson, S. M., Wig, G. S., Vogel, A. C., Lessov-Schlaggar, C. N., Barnes, K. A., Dubis, J. W., Feczko, E., Coalson, R. S., Pruett, J. R. J., Barch, D. M., Petersen, S. E., and Schlaggar, B. L. (2010). Prediction of individual brain maturity using fMRI. Science 329, 1358–1361
12. Jann, K., Smith, R. X., Rios Piedra, E. A., Dapretto, M., & Wang, D. J. J. (2016). Noise Reduction in Arterial Spin Labeling Based Functional Connectivity Using Nuisance Variables. Frontiers in Neuroscience, 10. https://doi.org/10.3389/fnins.2016.00371 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/460-01-006