562-06-008 ISMRM Abstract

Endogenous oxytocin release dynamically modulates fMRI connectivity

Primary: Brain Function and fMRI - Functional Connectivity

Secondary: Neuro - Neurotransmission

562-06-008 · fMRI: Preclinical · Wednesday, 13 May, 4:55 PM–5:50 PM · Digital Posters Row C

Keywords: Neurotransmission Dynamic Functional Connectivity Electrophysiological Connectivity Chemogenetics

Accepted

Alessandro Gozzi ¹, Caterina Montani¹, Andrew Hayward¹, Giovanni Morelli², Simone Malerba³, Yongsoo Kim⁴, Massimo Pasqualetti⁵, Stefano Panzeri³, Laura Cancedda², Elizabeth A De Guzman¹

¹Functional Neuorimaging Laboratory, Istituto Italiano di Tecnologia, Rovereto, Italy

²Istituto Italiano di Tecnologia, Rovereto, Italy

³University Medical Center Hamburg-Eppendorf, Hamburg, Germany

⁴The Pennsylvania State University, Hershey, Pennsylvania, United States of America

⁵University of Pisa, Pisa, Italy

Presenting Author: Alessandro Gozzi

Synopsis

Motivation:

Goals:

Approach:

Results:

Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

References

1. 1. Lefevre, A. et al. Oxytocinergic Feedback Circuitries: An Anatomical Basis for Neuromodulation of Social Behaviors. Front Neural Circuits 15, (2021).

2. 2. Stoop, R. Neuromodulation by Oxytocin and Vasopressin. Neuron 76, 142–159 (2012).

3. 3. Son, S. et al. Whole-Brain Wiring Diagram of Oxytocin System in Adult Mice. The Journal of Neuroscience 42, 5021–5033 (2022).

4. 4. Martins, D. A. et al. Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans. Nat Commun 11, 1160 (2020).

5. 5. Galbusera, A. et al. Intranasal Oxytocin and Vasopressin Modulate Divergent Brainwide Functional Substrates. Neuropsychopharmacology 42, 1420–1434 (2017).

6. 6.Gutierrez-Barragan, D., Ramirez, J. S. B., Panzeri, S., Xu, T. & Gozzi, A. Evolutionarily conserved fMRI network dynamics in the mouse, macaque, and human brain. Nat Commun 15, 8518 (2024).

7. 7.Giorgi, A. et al. Brain-wide Mapping of Endogenous Serotonergic Transmission via Chemogenetic fMRI. Cell Rep 21, 910–918 (2017).

8. 8.Wu, Z. et al. An Obligate Role of Oxytocin Neurons in Diet Induced Energy Expenditure. PLoS One 7, e45167 (2012).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/562-06-008