Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
366-06-012 ISMRM Abstract

Diffusion weighted imaging and Diffusion tensor imaging show cortical alterations in Systemic Lupus Erythematosus Patients

Primary: Neuro - Neuroinflammation
Secondary: Diffusion - DWI/DTI/DKI
366-06-012 · Body Diffusion MRI Applications · Monday, 11 May, 5:05 PM–6:00 PM · Digital Posters Row G
Keywords: Diagnosis/Prediction DWI/DTI/DKI Atrophy Cortical thickness Systemic Lupus Erythematosus
Accepted
Edin Zahirovic 1, Andreas Jönsen2, Zahra M Najeeb1, Anders Bengtsson2, Kristoffer Zervides2, Markus Nilsson1,3, Pia Maly Sundgren4,5,6,7
1Department of Diagnostic Radiology, Lund University, Lund, Sweden
2Department of Rheumatology, Lund University Hospital, Lund, Sweden
3Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden
4Lund University, Lund, Sweden
5Diagnostic Radiology, Lund University, Lund, Sweden
6Department of Medical Imaging and Physiology, Lund University Hospital, Lund, Sweden
7Medicinska fakulteten, Lund University Bioimaging Centre, Lund University, Lund, Sweden
Presenting Author: Edin Zahirovic

Synopsis

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References

1. Carter EE, Barr SG, Clarke AE. The global burden of SLE: prevalence, health disparities and socioeconomic impact. Nat Rev Rheumatol. 2016;12(10):605-20. DOI: 10.1038/nrrheum.2016.137 [doi]
2. Ainiala H, Loukkola J, Peltola J, Korpela M, Hietaharju A. The prevalence of neuropsychiatric syndromes in systemic lupus erythematosus. Neurology. 2001;57(3):496-500. DOI: 10.1212/wnl.57.3.496 [doi]
3. Galoppini G, Marangoni A, Cirilli F, Ruffilli F, Garaffoni C, Govoni M, et al. Optimizing Patient Care: A Systematic Review of Multidisciplinary Approaches for SLE Management. J Clin Med. 2023;12(12). DOI: 10.3390/jcm12124059 [doi]
4. Liu S, Cheng Y, Zhao Y, Yu H, Lai A, Lv Z, et al. Clinical Factors Associated with Brain Volume Reduction in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations. Front Psychiatry. 2018;9:8. PMID: 29449817 [pmid]
5. Liang SY, Wu YY, Chang NJ, Lai KL, Chen HM, Chen HC, et al. Cortical thickness and diffusion tensor imaging in patients with neuropsychiatric systemic lupus erythematosus, with normal structure on brain MRI. Lupus. 2023;32(4):489-99. DOI: 10.1177/09612033231155848 [doi]
6. Valdes Cabrera D, El Tal T, Mohamed I, Arciniegas SE, Fevrier S, Ledochowski J, et al. Effects of systemic lupus erythematosus on the brain: a systematic review of structural MRI findings and their relationships with cognitive dysfunction. Lupus Sci Med. 2024;11(2). DOI: 10.1136/lupus-2024-001214 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/366-06-012