452-01-001 / 452-01-001 ISMRM Abstract

Pediatric brain volumetry with SynthSeg: segmentation accuracy and influence of scan resolution and age

Primary: Pediatrics - Neuro

Secondary: Analysis Methods - Segmentation and Detection

452-01-001 · Pediatric Imaging Frontiers · Tuesday, 12 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2

Keywords: Segmentation Freesurfer Pediatric Brain Imaging Volumetry SynthSeg

Accepted

Rahel Heule ^1,2, Ruth O'Gorman Tuura^1,2

¹Center for MR Research, University Children's Hospital Zurich, Zurich, Switzerland

²Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland

Presenting Author: Rahel Heule

Synopsis

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References

1. Billot B, Greve DN, Puonti O, Thielscher A, Van Leemput K, Fischl B, Dalca AV, Iglesias JE, Adni. SynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retraining. Medical image analysis 2023;86. doi:10.1016/j.media.2023.102789 [doi]

2. Iglesias JE, Billot B, Balbastre Y, Magdamo C, Arnold SE, Das S, Edlow BL, Alexander DC, Golland P, Fischl B. SynthSR: A public AI tool to turn heterogeneous clinical brain scans into high-resolution T1-weighted images for 3D morphometry. Sci Adv 2023;9(5). doi:10.1126/sciadv.add3607 [doi]

3. Billot B, Magdamo C, Cheng Y, Arnold SE, Das S, Iglesias JE. Robust machine learning segmentation for large-scale analysis of heterogeneous clinical brain MRI datasets. Proceedings of the National Academy of Sciences of the United States of America 2023;120(9). doi:10.1073/pnas.2216399120 [doi]

4. Gopinath K, Greve DN, Das S, Arnold S, Magdamo C, Iglesias JE. Cortical Analysis of Heterogeneous Clinical Brain MRI Scans for Large-Scale Neuroimaging Studies. Medical Image Computing and Computer Assisted Intervention, Miccai 2023, Pt Viii 2023;14227:35-45. doi:10.1007/978-3-031-43993-3_4 [doi]

5. Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, van der Kouwe A, Killiany R, Kennedy D, Klaveness S, Montillo A, Makris N, Rosen B, Dale AM. Whole brain segmentation: Automated labeling of neuroanatomical structures in the human brain. Neuron 2002;33(3):341-355. doi:10.1016/S0896-6273(02)00569-X [doi]

6. Gopinath K, Greve DN, Magdamo C, Arnold S, Das S, Puonti O, Iglesias JE, Alzheimer's Disease Neuroimaging I. "Recon-all-clinical": Cortical surface reconstruction and analysis of heterogeneous clinical brain MRI. Medical image analysis 2025;103:103608. doi:10.1016/j.media.2025.103608 [doi]

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http://echo.ismrm.org/p/ISMRM2026/452-01-001