Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
562-05-010 ISMRM Abstract

T2* based Functional Mapping of the neonatal brain using Echo Planar Time-resolved Imaging at 7 Tesla

Primary: Pediatrics - Neonatal
Secondary: Contrast Mechanisms - Relaxometry
562-05-010 · Fetal and Neonatal Imaging · Wednesday, 13 May, 4:00 PM–4:55 PM · Digital Posters Row C
Keywords: fMRI (task based) EPTI 7T infant MRI Neonatal brain imaging T2star relaxometry
Accepted
Courtney Ormrod 1,2,3, David Leitão1,2,3, Daniel J West2,4, Antonia Massmann1,3,5, Jucha Willers Moore1,3, Inka Granlund3,4, Lucy Billimoria3,4, Pierluigi Di Cio3,4, Philippa Bridgen3,4, Alexandra Bonthrone1,3, Jonathan O'Muircheartaigh1,3,6, Jo V Hajnal1,2,3, Jian Wu7,8, Zijing Dong7,8, Fuyixue Wang7,8, Tomoki Arichi1,2,3,4,5, Shaihan Malik1,2,3
1Research Dept of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom
2Research Dept of Imaging Physics & Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom
3London Collaborative Ultra high field System (LoCUS), London, United Kingdom
4Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
5MRC Centre for Neurodevelopmental Disorders, King's College London, London, United Kingdom
6Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom
7Harvard Medical School, Boston, United States of America
8Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, United States of America
Presenting Author: Courtney Ormrod

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References

1. Pickles ES, Willers Moore J, Bridgen P, Uus A et al. Characterisation of brain T2* Values across the neonatal period at 7 Telsa. Proceedings of the International Society for Magnetic Resonance in Medicine. Vol. 0884. 2024.
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3. Wang F, Dong Z, Reese TG, et al. Echo planar time-resolved imaging (EPTI). Magn Reson Med. 2019 Jun;81(6):3599-3615. doi: 10.1002/mrm.27673. [doi]
4. Dong Z, Wang F, Reese TG, et al. Echo planar time-resolved imaging with subspace reconstruction and optimized spatiotemporal encoding. Magn Reson Med. 2020 Nov;84(5):2442-2455. doi: 10.1002/mrm.28295. [doi]
5. Wu J, Reese TG, Fujita S, Bilgic B, Wald LL, Dong Z, Wang F. Open EPTI: Pluggable, distortion-free continuous readout developed on Vendor-neutral Pulseq for versatile multi-contrast MR imaging. ISMRM 2025 p1274.
6. Malik SJ, Hand JW, Satnarine R, Price AN, Hajnal JV. Specific absorption rate and temperature in neonate models resulting from exposure to a 7T head coil. Magn Reson Med. 2021 Sep;86(3):1299-1313. doi: 10.1002/mrm.28784. Epub 2021 Apr 3. PMID: 33811667; PMCID: PMC7614747. [doi] [pmid]
7. Bridgen P, Tomi-Tricot R, Uus A, Cromb D et al. High resolution and contrast 7 tesla MR brain imaging of the neonate. Front Radiol. 2024 Jan 18;3:1327075. doi: 10.3389/fradi.2023.1327075. PMID: 38304343; PMCID: PMC10830693. [doi] [pmid]
8. Layton, K.J., Kroboth, S., Jia, F., Littin, S., Yu, H., Leupold, J., Nielsen, J.-F., Stöcker, T. and Zaitsev, M. (2017), Pulseq: A rapid and hardware-independent pulse sequence prototyping framework. Magn. Reson. Med., 77: 1544-1552. https://doi.org/10.1002/mrm.26235 [doi]
9. Brainard, D. H. (1997) The Psychophysics Toolbox, Spatial Vision 10:433-436.
10. Massmann A, Pickles ES, Bridgen P, Di Cio et al. Ultra-high field fMRI characterisation of cortical depth dependent BOLD responses in the primary visual cortex in neonates. Proceedings of the International Society for Magnetic Resonance in Medicine 2025.
11. Jenkinson, M., Beckmann, C. F., Behrens, T. E. J., Woolrich, M. W., & Smith, S. M. (2012). FSL. NeuroImage, 62(2), 782-790. https://doi.org/10.1016/j.neuroimage.2011.09.015 [doi]
12. Arichi T, Fagiolo G, Varela M, Melendez-Calderon A, Allievi A, Merchant N, Tusor N, Counsell SJ, Burdet E, Beckmann CF, Edwards AD. Development of BOLD signal hemodynamic responses in the human brain. Neuroimage. 2012 Nov 1;63(2):663-73. doi: 10.1016/j.neuroimage.2012.06.054. Epub 2012 Jul 6. PMID: 22776460; PMCID: PMC3459097. [doi] [pmid]

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http://echo.ismrm.org/p/ISMRM2026/562-05-010