Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
406-02-003 ISMRM Abstract

Rapid Tissue-CSF Exchange in the Perivascular Space Detected by Magnetization Transfer Indirect Spin Labeling

Primary: Neuro - Neurofluids
Secondary: Contrast Mechanisms - Novel Contrast Mechanisms
406-02-003 · The Dynamic Brain: Flow, Pressure, and Exchange · Tuesday, 12 May, 1:40 PM–3:30 PM · Auditorium 2
Keywords: Cerebrospinal fluid Glymphatic system function Tissue-CSF water exchange Magnetization transfer indirect spin labeling Perivascular spaces (PVS)
Accepted
Yihan Wu 1, Kexin Wang1, Licheng Ju2,3, Anna M Li3, Qin Qin4, Feng Xu2, Doris Lin2, Lawrence Kleinberg5, Jiadi Xu2,3
1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, United States of America
2Johns Hopkins University School of Medicine, Baltimore, United States of America
3F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, United States of America
4Department of Radiology, University of Washington School of Medicine, SEALLTE, United States of America
5Department of Radiation Oncology and Radiation Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, United States of America
Presenting Author: Yihan Wu

Synopsis

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References

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6. Li AM, Chen L, Liu H, Li Y, Duan W, Xu J. Age-dependent cerebrospinal fluid-tissue water exchange detected by magnetization transfer indirect spin labeling MRI. Magn Reson Med 2022;87(5):2287-2298. doi: 10.1002/mrm.29137 [doi]
7. Manera AL, Dadar M, Fonov V, Collins DL. CerebrA, registration and manual label correction of Mindboggle-101 atlas for MNI-ICBM152 template. Scientific Data 2020;7(1):237. doi: 10.1038/s41597-020-0557-9 [doi]
8. Kim D, Huang Y, Liu J. Non-invasive MRI measurements of age-dependent in vivo human glymphatic exchange using magnetization transfer spin labeling. Neuroimage 2025;310:121142. doi: 10.1016/j.neuroimage.2025.121142 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/406-02-003