Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
461-01-008 ISMRM Abstract

Towards Consistent Myocardial T1 and T2 Mapping: A Phantom-Based Harmonization Method

Primary: Cardiovascular - Myocardium
Secondary: Acquisition & Reconstruction - Quantitative Imaging: relaxometry, multi-parametric, MR Fingerprinting, and synthetic MRI
461-01-008 · Cardiac Tissue Characterization · Tuesday, 12 May, 8:20 AM–9:15 AM · Digital Posters Row B
Keywords: T1 Mapping Harmonization MOLLI T1 Saturation recovery Phantom-Based Calibration
Accepted
Utsav Shrestha1, Julius F Heidenreich 1,2, Jeff Kammerman3, David R Rutkowski3, David T Harris1, Diego Hernando1,4,5,6, Jean H Brittain3, Scott B Reeder1,4,5,7,8
1Department of Radiology, University of Wisconsin - Madison, Madison, United States of America
2Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany
3Calimetrix, Madison, United States of America
4Department of Medical Physics, University of Wisconsin - Madison, Madison, United States of America
5Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, United States of America
6Department of Electrical and Computer Engineering, University of Wisconsin - Madison, Madison, United States of America
7Department of Medicine, University of Wisconsin - Madison, Madison, United States of America
8Department of Emergency Medicine, University of Wisconsin - Madison, Madison, United States of America
Presenting Author: Julius F Heidenreich

Synopsis

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References

1. Roth GA, Johnson CO, Abate KH, et al. The burden of cardiovascular diseases among us states, 1990-2016. JAMA Cardiol. 2018;3(5):375-389. doi:10.1001/jamacardio.2018.0385 [doi]
2. Kellman P, Hansen MS. T1-Mapping in the Heart: Accuracy and Precision.; 2014. http://jcmr-online.com/content/16/1/2.
3. Kellman P, Arai AE, Xue H. T1 and Extracellular Volume Mapping in the Heart: Estimation of Error Maps and the Influence of Noise on Precision.; 2013. http://www.jcmr-online.com/content/15/1/56.
4. Captur G, Gatehouse P, Keenan KE, et al. A medical device-grade T1 and ECV phantom for global T1 mapping quality assurance - the T1 Mapping and ECV Standardization in cardiovascular magnetic resonance (T1MES) program. Journal of Cardiovascular Magnetic Resonance. 2016;18(1):1-20. doi:10.1186/s12968-016-0280-z [doi]
5. Captur G, Bhandari A, Brühl R, et al. T 1 mapping performance and measurement repeatability: Results from the multi-national T 1 mapping standardization phantom program (T1MES). Journal of Cardiovascular Magnetic Resonance. 2020;22(1). doi:10.1186/s12968-020-00613-3 [doi]
6. Zhang Q, Werys K, Popescu IA, et al. Quality assurance of quantitative cardiac T1-mapping in multicenter clinical trials – A T1 phantom program from the hypertrophic cardiomyopathy registry (HCMR) study. Int J Cardiol. 2021;330:251-258. doi:10.1016/j.ijcard.2021.01.026 [doi]
7. Suh YJ, Kim PK, Park J, Park EA, Jung JI, Choi BW. Phantom-based correction for standardization of myocardial native T1 and extracellular volume fraction in healthy subjects at 3-Tesla cardiac magnetic resonance imaging. Eur Radiol. 2022;32(12):8122-8130. doi:10.1007/s00330-022-08936-8 [doi]
8. Xu Z, Li W, Wang J, et al. Reference ranges of myocardial T1 and T2 mapping in healthy Chinese adults: a multicenter 3.0T cardiovascular magnetic resonance study. Journal of Cardiovascular Magnetic Resonance. 2023;25(1). doi:10.1186/s12968-023-00974-5 [doi]
9. Meloni A, Nicola M, Positano V, et al. Myocardial T2 values at 1.5 T by a segmental approach with healthy aging and gender. Eur Radiol. 2022;32(5):2962-2975. doi:10.1007/s00330-021-08396-6 [doi]
10. Robson MD, Piechnik SK, Tunnicliffe EM, Neubauer S. T1 measurements in the human myocardium: The effects of magnetization transfer on the SASHA and MOLLI sequences. Magn Reson Med. 2013;70(3):664-670. doi:10.1002/mrm.24867 [doi]
11. Lockard C, Tu R yuan, Yan K, et al. Cardiac Phantom-based Inter-site Calibration of T2, T1, and ECV Measurements. In: 2024 ISMRM & ISMRT Annual Meeting. ISMRM; 2024. doi:10.58530/2024/1496 [doi]
12. Piechnik SK, Ferreira VM, Dall’Armellina E, et al. Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold. Journal of Cardiovascular Magnetic Resonance. 2010;12(1). doi:10.1186/1532-429X-12-69 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/461-01-008