Yiran Li1, Bo Li1, Xiao Liang1, TIANYAO WANG2, Manuel Taso3, Amnah Mahroo4,5, Lucas Lemos Franco1, Yulin Chang3, Maria Fernandez-Seara6, Matthias Günther4,7,8, John Detre9,10, Ze Wang 1
1Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, United States of America
2Department of Radiology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, China
3Siemens Medical Solutions USA, Inc., Malvern, United States of America
4Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany
5University Health Network, Toronto, Canada
6Department of Radiology, Clínica Universidad de Navarra, Spain, Spain
7Universität Bremen, Bremen, Germany
8mediri GmbH, Heidelberg, Germany
9Department of Neurology, University of Pennsylvania, Philadelphia, United States of America
10Department of Radiology, University of Pennsylvania, Philadelphia, United States of America
Presenting Author: Ze Wang
Synopsis
Motivation:
Goals:
Approach:
Results:
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
1. Abdullahi W, Tripathi D, Ronaldson PT. Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection. Am J Physiol Cell Physiol 2018;315(3):C343-C356.
2. Sweeney MD, Zhao Z, Montagne A, Nelson AR, Zlokovic BV. Blood-Brain Barrier: From Physiology to Disease and Back. Physiol Rev 2019;99(1):21-78.
3. Gregori J, Schuff N, Kern R, Gunther M. T2-based arterial spin labeling measurements of blood to tissue water transfer in human brain. J Magn Reson Imaging 2013;37(2):332-342.
4. Ohene Y, Harrison IF, Evans PG, Thomas DL, Lythgoe MF, Wells JA. Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE ASL MRI. Magn Reson Med 2021;85(1):326-333.
5. Wells JA, Siow B, Lythgoe MF, Thomas DL. Measuring biexponential transverse relaxation of the ASL signal at 9.4 T to estimate arterial oxygen saturation and the time of exchange of labeled blood water into cortical brain tissue. J Cereb Blood Flow Metab 2013;33(2):215-224.
6. Mahroo A, Buck MA, Huber J, Breutigam NJ, Mutsaerts H, Craig M, Chappell M, Gunther M. Robust Multi-TE ASL-Based Blood-Brain Barrier Integrity Measurements. Front Neurosci 2021;15:719676.
7. Lingala SG, Hu Y, DiBella E, Jacob M. Accelerated Dynamic MRI Exploiting Sparsity and Low-Rank Structure: k-t SLR. IEEE Transactions on Medical Imaging 2011;30(5):1042-1054.
8. Petzschner FH, Ponce IP, Blaimer M, Jakob PM, Breuer FA. Fast MR parameter mapping using k-t principal component analysis. Magn Reson Med 2011;66(3):706-716.
9. Huang C, Graff CG, Clarkson EW, Bilgin A, Altbach MI. T2 mapping from highly undersampled data by reconstruction of principal component coefficient maps using compressed sensing. Magn Reson Med 2012;67(5):1355-1366.
10. Zhao B, Lu W, Hitchens TK, Lam F, Ho C, Liang ZP. Accelerated MR parameter mapping with low-rank and sparsity constraints. Magn Reson Med 2015;74(2):489-498.
11. Doneva M, Bornert P, Eggers H, Stehning C, Senegas J, Mertins A. Compressed sensing reconstruction for magnetic resonance parameter mapping. Magn Reson Med 2010;64(4):1114-1120.
12. Zhang T, Pauly JM, Levesque IR. Accelerating parameter mapping with a locally low rank constraint. Magn Reson Med 2015;73(2):655-661.
13. Donoho DL. Compressed sensing. IEEE Transactions on Information Theory 2006;52(4):1289-1306.
14. E Candès JR, T Tao. Robust uncertainty principles: exact signal reconstruction from highly incomplete frequency information. IEEE Trans Inf Theory 2006;52:489–509.
15. Block KT, Uecker M, Frahm J. Undersampled radial MRI with multiple coils. Iterative image reconstruction using a total variation constraint. Magnetic Resonance in Medicine 2007;57(6):1086-1098.
16. Lustig M, Donoho D, Pauly JM. Sparse MRI: The application of compressed sensing for rapid MR imaging. Magn Reson Med 2007;58(6):1182-1195.
17. Gamper U, Boesiger P, Kozerke S. Compressed sensing in dynamic MRI. Magnetic Resonance in Medicine 2008;59(2):365-373.
18. Li B, Li Y, Liu H, Franco L, Taso M, Tisdall D, Chang Y, Detre J, Wang Z. ASL MRI with echo-resolved 3D TSE Stack-of-Spirals readout. 2025 ISMRM Workshop on Perfusion MRI; Pamplona, Spain.
19. Fessler JA, Sutton BP. Nonuniform fast Fourier transforms using min-max interpolation. IEEE Transactions on Signal Processing 2003;51(2):560-574.
20. Chappell MA, Groves AR, Whitcher B, Woolrich MW. Variational Bayesian inference for a nonlinear forward model. IEEE Trans Signal Process 2008;57:14.