Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
566-02-001 ISMRM Abstract

Image quality assessment of a comprehensive ultra-fast MRI protocol for dementia diagnosis and monitoring

Primary: Neuro - Dementia
Secondary: Analysis Methods - Data Processing
566-02-001 · MRI Markers of Dementia · Wednesday, 13 May, 9:15 AM–10:10 AM · Digital Posters Row G
Keywords: Dementia Image Quality Assessment Wave-CAIPI Image Quality Metrics Ultra-fast brain MRI
Accepted
Haroon R Chughtai 1,2,3, David L Thomas4,5, Miguel Rosa-Grilo4, Carole H Sudre1,6,7,8, Bhavana S Solanky1,3,9, Millie Beament4, Daniel Nicolas Splitthoff10, Daniel C Alexander1,7, Frederik Barkhof1,4,11,12, Nick C. Fox4, Catherine J. Mummery4, Geoff J Parker1,3,13
1UCL Hawkes Institute, University College London, London, United Kingdom
2Advanced Research Computing Centre, University College London, London, United Kingdom
3Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom
4Dementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom
5Department of Translational Neuroscience and Stroke, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom
6Unit for Lifelong Health and Ageing, Department of Population Science and Experimental Medicine, University College London, London, United Kingdom
7Department of Computer Science, University College London, London, United Kingdom
8School of Biomedical Engineering and Imaging Sciences, Kings College London, London, United Kingdom
9NMR Research unit, Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom
10Research & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany
11Department of Radiology & Nuclear Medicine, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
12Queen Square Institute of Neurology, University College London, London, United Kingdom
13Bioxydyn Limited, Manchester, United Kingdom
Presenting Author: Haroon R Chughtai

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References

1. Živanović M, Trenkić AA, Milošević V, Stojanov D, Mišić M, Radovanović M, Radovanović V. The role of magnetic resonance imaging in the diagnosis and prognosis of dementia. Biomol Biomed. 2023;23(2):209-224. doi:10.17305/bjbms.2022.8085 [doi]
2. Harper L, Barkhof F, Scheltens P, Schott JM, Fox NC. An algorithmic approach to structural imaging in dementia. J Neurol Neurosurg Psychiatry. 2014;85(6):692-698. doi:10.1136/jnnp-2013-306285 [doi]
3. Bilgic B, Gagoski BA, Cauley SF, Fan AP, Polimeni JR, Grant PE, Wald LL, Setsompop K. Wave-CAIPI for highly accelerated 3D imaging. Magn Reson Med. 2015;73(6):2152-2162. doi:10.1002/mrm.25347 [doi]
4. Rosa-Grilo M, Chughtai HR, Thomas DL, Alexander DC, Beament M, Belder CRS, Jäger HR, Lim EA, Magill N, Mallon D, Nicholas JM, Nicholas O, Urban F, Parker GJM, Barkhof F, Mummery CJ, Fox NC. Ultra-fast MRI for dementia diagnosis and treatment eligibility: A prospective study. Alzheimers Dement. 2025;21(6):e70341. doi:10.1002/alz.70341 [doi]
5. Chughtai HR, Thomas DL, Rosa-Grilo M, Sudre CH, Solanky BS, Lim E, Mallon D, Jäger HR, Prosser L, Malone IB, others. Clinical validation of a multi-modal ultra-fast MRI protocol for dementia diagnosis. In: ISMRM & ISMRT Annual Meeting & Exhibition. 2025. https://archive.ismrm.org/2025/0568.html
6. Fischl B. FreeSurfer. NeuroImage. 2012;62(2):774-781. doi:10.1016/j.neuroimage.2012.01.021 [doi]
7. Dietrich O, Raya JG, Reeder SB, Reiser MF, Schoenberg SO. Measurement of signal-to-noise ratios in MR images: Influence of multichannel coils, parallel imaging, and reconstruction filters. J Magn Reson Imaging. 2007;26(2):375-385. doi:10.1002/jmri.20969 [doi]
8. Sudre CH, Cardoso MJ, Bouvy WH, Biessels GJ, Barnes J, Ourselin S. Bayesian model selection for pathological neuroimaging data applied to white matter lesion segmentation. IEEE Trans Med Imaging. 2015;34(10):2079-2102. doi:10.1109/TMI.2015.2419072 [doi]
9. Sudre CH, Chughtai HR, Thomas DL, Cash D, Rosa-Grilo M, Mummery CJ, Fox NC, Parker GJM. Ultra rapid volumetric imaging for diagnosis in memory clinic: assessment of white matter hyperintensities quantification. In: ISMRM & ISMRT Annual Meeting & Exhibition.

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/566-02-001