2Department of Radiology, Huaxi MR Research Center (HMRRC), Institute of Radiology and Medical Imaging, West China Hospital of Sichuan University, Chengdu, China
3Psychoradiology Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China
4Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, China
5GE HealthCare MR Research, Beijing, China
6West China Hospital of Sichuan University, Chendu, China
7Department of Anesthesiology, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, China
Presenting Author: Qiao Wen
Synopsis
Motivation:
Goals:
Approach:
Results:
Full abstract & presentation
The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.
Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.
To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.
1. Zacharias HU, Weihs A, Habes M, Wittfeld K, Frenzel S, Rashid T, Stubbe B, Obst A, Szentkirályi A, Bülow R, Berger K, Fietze I, Penzel T, Hosten N, Ewert R, Völzke H, Grabe HJ. Association Between Obstructive Sleep Apnea and Brain White Matter Hyperintensities in a Population-Based Cohort in Germany. JAMA network open 2021;4(10):e2128225.https://doi.org/10.1001/jamanetworkopen.2021.28225 [doi]
2. Zhang H, Peng L, Wang Y, Zhao W, Lau WB, Wang Y, Li Y, Du Y, Li L, Huang Y, Nie S, Qin Y, Ma X, Wei Y. Extracellular vesicle-derived miR-144 as a novel mechanism for chronic intermittent hypoxia-induced endothelial dysfunction. Theranostics 2022;12(9):4237-4249.https://doi.org/10.7150/thno.69035 [doi]
3. Bubu OM, Andrade AG, Umasabor-Bubu OQ, Hogan MM, Turner AD, de Leon MJ, Ogedegbe G, Ayappa I, Jean-Louis GG, Jackson ML, Varga AW, Osorio RS. Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary research. Sleep medicine reviews 2020;50:101250.https://doi.org/10.1016/j.smrv.2019.101250 [doi]
4. Gong LJ, Wang XY, Gu WY, Wu X. Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea. Journal of neuroinflammation 2020;17(1):337.https://doi.org/10.1186/s12974-020-02014-w [doi]
5. Gharib SA, Hurley AL, Rosen MJ, Spilsbury JC, Schell AE, Mehra R, Patel SR. Obstructive sleep apnea and CPAP therapy alter distinct transcriptional programs in subcutaneous fat tissue. Sleep 2020;43(6).https://doi.org/10.1093/sleep/zsz314 [doi]
6. Marchi NA, Pizzarotti B, Solelhac G, Berger M, Haba-Rubio J, Preisig M, Vollenweider P, Marques-Vidal P, Lutti A, Kherif F, Heinzer R, Draganski B. Abnormal brain iron accumulation in obstructive sleep apnea: A quantitative MRI study in the HypnoLaus cohort. Journal of sleep research 2022;31(6):e13698.https://doi.org/10.1111/jsr.13698 [doi]
7. Bai M, Xiong Z, Zhang Y, Wang Z, Zeng X. Associations between quantitative susceptibility mapping with male obstructive sleep apnea clinical and imaging markers. Sleep medicine 2024;124:154-161.https://doi.org/10.1016/j.sleep.2024.09.019 [doi]
8. Mohammadi M, Samadi S, Batouli SAH, Pestei K, Oghabian MA. Reduced Oxygen Extraction Fraction as a Biomarker for Cognitive Deficits in Obstructive Sleep Apnea. Brain and behavior 2025;15(2):e70273.https://doi.org/10.1002/brb3.70273 [doi]
9. Bilgic B, Costagli M, Chan KS, Duyn J, Langkammer C, Lee J, Li X, Liu C, Marques JP, Milovic C, Robinson SD, Schweser F, Shmueli K, Spincemaille P, Straub S, van Zijl P, Wang Y. Recommended implementation of quantitative susceptibility mapping for clinical research in the brain: A consensus of the ISMRM electro-magnetic tissue properties study group. Magnetic resonance in medicine 2024;91(5):1834-1862.https://doi.org/10.1002/mrm.30006 [doi]
10. Tian Y, Margulies DS, Breakspear M, Zalesky A. Topographic organization of the human subcortex unveiled with functional connectivity gradients. Nature neuroscience 2020;23(11):1421-1432.https://doi.org/10.1038/s41593-020-00711-6 [doi]
11. Howard CM, Jain S, Cook AD, Packard LE, Mullin HA, Chen NK, Liu C, Song AW, Madden DJ. Cortical iron mediates age-related decline in fluid cognition. Human brain mapping 2022;43(3):1047-1060.https://doi.org/10.1002/hbm.25706 [doi]
12. Wimmer I, Scharler C, Kadowaki T, Hillebrand S, Scheiber-Mojdehkar B, Ueda S, Bradl M, Berger T, Lassmann H, Hametner S. Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low-grade haemolysis of fragile macrocytic red blood cells. Brain pathology (Zurich, Switzerland) 2021;31(2):333-345.https://doi.org/10.1111/bpa.12920 [doi]
13. Thomas GEC, Leyland LA, Schrag AE, Lees AJ, Acosta-Cabronero J, Weil RS. Brain iron deposition is linked with cognitive severity in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry 2020;91(4):418-425.https://doi.org/10.1136/jnnp-2019-322042 [doi]
14. Andrews DS, Aksman L, Kerns CM, Lee JK, Winder-Patel BM, Harvey DJ, Waizbard-Bartov E, Heath B, Solomon M, Rogers SJ, Altmann A, Nordahl CW, Amaral DG. Association of Amygdala Development With Different Forms of Anxiety in Autism Spectrum Disorder. Biological psychiatry 2022;91(11):977-987.https://doi.org/10.1016/j.biopsych.2022.01.016 [doi]