Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
405-04-006 ISMRM Abstract

Shared and specific submillimeter cortical radial diffusion changes in schizophrenia and bipolar disorder

Primary: Diffusion - DWI/DTI/DKI
Secondary: Analysis Methods - Image Registration and Alignment
405-04-006 · From Diffusion Characteristics Toward Clinical Impact · Tuesday, 12 May, 4:00 PM–5:50 PM · Ballroom West
Keywords: Schizophrenia Bipolar disorder High-Resolution MRI Diffusion Tensor Imaging (DTI) Brain cortex
Accepted
Xing Li 1, Jiaxin Zeng1, Naici Liu1, Huilou Liang2, Wenjing Zhang1, Su Lui3
1West China Hospital of Sichuan University, Chendu, China
2GE HealthCare MR Research, Beijing, China
3West China Hospital, Sichuan University, China
Presenting Author: Xing Li

Synopsis

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References

1. Hoffmann J, Meller T, Maj C, Hoffmann P, Forstner AJ, Nöthen MM, et al. Differential Association of Schizotypy Dimensions With Brain Structural Connectivity and Moderation by Schizophrenia Polygenic Risk. Schizophrenia bulletin. 2025;51(Suppl 2):S149-s59. doi: 10.1093/schbul/sbae160 [doi]
2. Nazeri A, Mulsant BH, Rajji TK, Levesque ML, Pipitone J, Stefanik L, et al. Gray Matter Neuritic Microstructure Deficits in Schizophrenia and Bipolar Disorder. Biological psychiatry. 2017;82(10):726-36. doi: 10.1016/j.biopsych.2016.12.005 [doi]
3. Huang S, Lee H, Ma Y, Chan KS, Krijnen E, Eskandarian L, et al. Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI. Research square. 2025. doi: 10.21203/rs.3.rs-6724971/v1 [doi]
4. Zhang J, Sun Z, Duan F, Shi L, Zhang Y, Solé-Casals J, et al. Cerebral cortex layer segmentation using diffusion magnetic resonance imaging in vivo with applications to laminar connections and working memory analysis. Human brain mapping. 2022;43(17):5220-34. doi: 10.1002/hbm.25998 [doi]
5. Chen NK, Guidon A, Chang HC, Song AW. A robust multi-shot scan strategy for high-resolution diffusion weighted MRI enabled by multiplexed sensitivity-encoding (MUSE). NeuroImage. 2013;72:41-7. doi: 10.1016/j.neuroimage.2013.01.038 [doi]
6. McNab JA, Polimeni JR, Wang R, Augustinack JC, Fujimoto K, Stevens A, et al. Surface based analysis of diffusion orientation for identifying architectonic domains in the in vivo human cortex. NeuroImage. 2013;69:87-100. doi: 10.1016/j.neuroimage.2012.11.065 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/405-04-006