Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
469-04-009 ISMRM Abstract

Assessing feasibility of mapping skeletal muscle mitochondrial oxidative phosphorylation in upper limbs

Primary: Musculoskeletal - Other Musculoskeletal
Secondary: Acquisition & Reconstruction - Non-AI methods
469-04-009 · MRI and MRS in Muscle in Health and Disease · Tuesday, 12 May, 2:35 PM–3:30 PM · Digital Posters Row J
Keywords: Phosphocreatine Creatine CEST MRI Oxidative phosphorylation
Accepted
Ritambhar Burman1, Ongira Chowdhury1, Jennifer Valley1, Asim Bag1, Yuxi Pang 1, Puneet Bagga1
1Department of Radiology, St. Jude Children's Research Hospital, Memphis, United States of America
Presenting Author: Yuxi Pang

Synopsis

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References

1. Schur, G. M., J. Dunn, S. Nguyen, A. Dedio, K. Wade, J. Tamaroff, N. Mitta, et al. "In Vivo Assessment of Oxphos Capacity Using 3 T Crcest Mri in Friedreich's Ataxia." J Neurol 269, no. 5 (May 2022): 2527-38. https://doi.org/10.1007/s00415-021-10821-1. https://www.ncbi.nlm.nih.gov/pubmed/34652504. [doi] [pmid]
2. Habets, L. E., B. Bartels, F. L. Asselman, M. T. Hooijmans, S. van den Berg, A. J. Nederveen, W. L. van der Pol, and J. A. L. Jeneson. "Magnetic Resonance Reveals Mitochondrial Dysfunction and Muscle Remodelling in Spinal Muscular Atrophy." Brain 145, no. 4 (May 24 2022): 1422-35. https://doi.org/10.1093/brain/awab411. https://www.ncbi.nlm.nih.gov/pubmed/34788410. [doi] [pmid]
3. Howard, J.W., G Shields, G Gambarota, R.M. Gordon, A.W. Rao, and R.D. Newbould. "31p Mrs of the Biceps Brachii Muscle at 3t." Paper presented at the International Society of Magnetic Resonance in Medicine, Stockholm, Sweden, 2010.
4. Meyerspeer, M., C. Boesch, D. Cameron, M. Dezortova, S. C. Forbes, A. Heerschap, J. A. L. Jeneson, et al. "(31) P Magnetic Resonance Spectroscopy in Skeletal Muscle: Experts' Consensus Recommendations." NMR Biomed 34, no. 5 (Feb 10 2020): e4246. https://doi.org/10.1002/nbm.4246. https://www.ncbi.nlm.nih.gov/pubmed/32037688. [doi] [pmid]
5. Burman, R., Y. Pang, A. Bag, R. S. Finkel, K. K. Ness, and P. Bagga. "A Novel Cest-Based Approach for Reliably Assessing Skeletal Muscle Oxidative Phosphorylation: Oxcest." Magn Reson Med (Oct 22 2025). https://doi.org/10.1002/mrm.70133. https://www.ncbi.nlm.nih.gov/pubmed/41126538. [doi] [pmid]
6. Fleischman, A., H. Makimura, T. L. Stanley, M. A. McCarthy, M. Kron, N. Sun, S. Chuzi, et al. "Skeletal Muscle Phosphocreatine Recovery after Submaximal Exercise in Children and Young and Middle-Aged Adults." J Clin Endocrinol Metab 95, no. 9 (Sep 2010): E69-74. https://doi.org/10.1210/jc.2010-0527. https://www.ncbi.nlm.nih.gov/pubmed/20554709. [doi] [pmid]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/469-04-009