362-04-004 ISMRM Abstract

Investigating Diurnal Changes in Metabolite Ratios in the Human Brain Using 7T MRSI

Primary: Contrast Mechanisms - Spectroscopy

Secondary: Acquisition & Reconstruction - Spectroscopy and spectroscopic imaging

362-04-004 · Spectroscopy and Spectroscopic Imaging: Neuro I · Monday, 11 May, 2:45 PM–3:40 PM · Digital Posters Row C

Keywords: 7 Tesla Metabolic imaging Reproducibility Magnetic resonance spectroscopic imaging Diurnal variation

Accepted

Philipp Lazen ¹, Sara Huskic¹, Ahmet Azgın¹, Sagar Acharya^1,2, Bernhard Strasser¹, Lukas Hingerl¹, Wolfgang Bogner^1,2, Gilbert Hangel¹, Karl Rössler^1,2,3

¹Medical University of Vienna, Vienna, Austria

²Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

³Comprehensive Center for Clinical Neurosciences & Mental Health, Medical University of Vienna, Vienna, Austria

Presenting Author: Philipp Lazen

Synopsis

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References

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2. Lazen, P. Evaluating the Stability of 7 Tesla Whole-Brain Magnetic Resonance Spectroscopic Imaging in Volunteers and Tumor Patients, Medical University of Vienna, Vienna, Austria, 2025. http://repositorium.meduniwien.ac.at/obvumwhs/12287736 (accessed 2025-10-28).

3. Volk, C.; Jaramillo, V.; Merki, R.; O’Gorman Tuura, R.; Huber, R. Diurnal Changes in Glutamate + Glutamine Levels of Healthy Young Adults Assessed by Proton Magnetic Resonance Spectroscopy. Hum Brain Mapp 2018, 39 (10), 3984–3992. https://doi.org/10.1002/hbm.24225. [doi]

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5. Giraud, C.; Poinas, A.; Bonnin, L.; Pellerin, L.; Guillevin, C.; Guillevin, R. Time-of-Day Study on Brain Metabolism Using Proton Magnetic Resonance Spectroscopy. Journal of Neuroradiology 2026, 53 (1), 101395. https://doi.org/10.1016/j.neurad.2025.101395. [doi]

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7. Hangel, G.; Spurny-Dworak, B.; Lazen, P.; Cadrien, C.; Sharma, S.; Hingerl, L.; Hečková, E.; Strasser, B.; Motyka, S.; Lipka, A.; Gruber, S.; Brandner, C.; Lanzenberger, R.; Rössler, K.; Trattnig, S.; Bogner, W. Inter-Subject Stability and Regional Concentration Estimates of 3D-FID-MRSI in the Human Brain at 7 T. NMR Biomed 2021, 34 (12), e4596. https://doi.org/10.1002/nbm.4596. [doi]

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9. Chambers, S.; Lazen, P.; Hotka, M.; Shayeste, H.; Tomschik, M.; Wais, J.; Zeiser, V.; Hingerl, L.; Strasser, B.; Haider, L.; Traub‐Weidinger, T.; Baumgartner, C.; Koren, J.; Mayer, F.; Feucht, M.; Dorfer, C.; Pataraia, E.; Bogner, W.; Trattnig, S.; Kasprian, G.; Rössler, K.; Hangel, G. Glutamine Metabolism and Metabolic Profiling Using 7 T CRT‐FID MRSI in Focal Epilepsy. Eur J Neurol 2025, 32 (9), e70343. https://doi.org/10.1111/ene.70343. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/362-04-004