Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
667-04-003 ISMRM Abstract

Cortical Bone Matrix and Porosity Assessment in Osteoporosis and CKD-MBD Using Novel 3D UTE-MRI Biomarkers

Primary: Musculoskeletal - Bone
Secondary: Acquisition & Reconstruction - Quantitative Imaging: spine, MSK, others
667-04-003 · Novel Visualization and Assessment of Osseous Tissues · Thursday, 14 May, 2:35 PM–3:30 PM · Digital Posters Row H
Keywords: Bone Quantitative MRI Osteoporosis UTE-MRI Quantitative imaging biomarkers
Accepted
Arya A Suprana1,2, Yankai Meng1,3, Jisook Yi1,4, Jiayang Wu1,5, Jiaji Wang1,6, Jiyo S Athertya1, Soo Hyun Shin1, Robert L Sah2, Yajun Ma1, Saeed Jerban1, Charles Ginsberg7, Gina N Woods1, Jiang Du 1,2,8
1University of California, Berkeley, United States of America
2Shu Chien-Gene Lay Department of Bioengineering, University of California, San Diego, La Jolla, United States of America
3Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
4Department of Radiology, Inje University Haeundae Paik Hospital, Busan, Korea, Republic of
5Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, China
6Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
7Department of Medicone, Division of Nephrology-Hypertension, University of California, San Diego, United States of America
8Radiology Service, VA San Diego Healthcare System, La Jolla, California, San Diego, United States of America
Presenting Author: Jiang Du

Synopsis

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References

1. 1. Hsu CY, Chen LR, Chen KH. Osteoporosis in Patients with Chronic Kidney Diseases: A Systemic Review. Int J Mol Sci. 2020;21(18). doi:10.3390/ijms21186846 [doi]
2. 2. Shin SH, Chae HD, Suprana A, et al. UTE MRI technical developments and applications in osteoporosis: a review. Front Endocrinol (Lausanne). 2025;16:1510010. doi:10.3389/fendo.2025.1510010 [doi]
3. 3. Wehrli FW, Song HK, Saha PK, Wright AC. Quantitative MRI for the assessment of bone structure and function. NMR Biomed. 2006;19(7):731-764. doi:10.1002/nbm.1066 [doi]
4. 4. Jerban S, Jang H, Chang EY, Bukata S, Du J, Chung CB. Bone Biomarkers Based on Magnetic Resonance Imaging. Semin Musculoskelet Radiol. 2024;28(1):62-77. doi:10.1055/s-0043-1776431 [doi]
5. 5. Granke M, Does MD, Nyman JS. The Role of Water Compartments in the Material Properties of Cortical Bone. Calcif Tissue Int. 2015;97(3):292-307. doi:10.1007/s00223-015-9977-5 [doi]
6. 6. Jerban S, Ma Y, Moazamian D, et al. MRI-based porosity index (PI) and suppression ratio (SR) in the tibial cortex show significant differences between normal, osteopenic, and osteoporotic female subjects. Front Endocrinol (Lausanne). 2023;14:1148345. doi:10.3389/fendo.2023.1148345 [doi]
7. 7. Rajapakse CS, Bashoor-Zadeh M, Li C, Sun W, Wright AC, Wehrli FW. Volumetric Cortical Bone Porosity Assessment with MR Imaging: Validation and Clinical Feasibility. Radiology. 2015;276(2):526-535. doi:10.1148/radiol.15141850 [doi]
8. 8. Li C, Seifert AC, Rad HS, et al. Cortical bone water concentration: dependence of MR imaging measures on age and pore volume fraction. Radiology. 2014;272(3):796-806. doi:10.1148/radiol.14132585 [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/667-04-003