Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
660-03-002 ISMRM Abstract

RF Power Amplifier Drift Compensation for CEST MRI

Primary: Contrast Mechanisms - CEST / APT / NOE
Secondary: Physics & Engineering - High-Field MRI
660-03-002 · Advances in Chemical Exchange MRI: CEST, APT, and NOE I · Thursday, 14 May, 1:40 PM–2:35 PM · Digital Posters Row A
Keywords: System Imperfections: Measurement & Correction Ultra-high field CEST MRI RF power amplifier RFPA Drift
Accepted
Ali Aghaeifar1, Desmond Tse2,3, Dimo Ivanov 2,3, Klaus Scheffler4,5, Patrick Liebig6
1MR Collaborations, Siemens Healthineers, Erlangen, Germany
2Cooperative Brain Imaging Center (CoBIC), Frankfurt, Germany
3Research Group Structural and Physiological Imaging with High-Field MRI, Max Planck Institute for Empirical Aesthetics, Frankfurt am Main, Germany
4Max Planck Institute for Biological Cybernetics, Tübingen, Germany
5Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany
6MR Application Predevelopment, Siemens Healthineers, Erlangen, Germany
Presenting Author: Dimo Ivanov

Synopsis

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References

1. Near, J.; Edden, R.; Evans, C. J.; Paquin, R.; Harris, A.; Jezzard, P. Frequency and Phase Drift Correction of Magnetic Resonance Spectroscopy Data by Spectral Registration in the Time Domain. Magn. Reson. Med. 2015, 73 (1), 44–50. https://doi.org/10.1002/mrm.25094. [doi]
2. Vos, S. B.; Tax, C. M. W.; Luijten, P. R.; Ourselin, S.; Leemans, A.; Froeling, M. The Importance of Correcting for Signal Drift in Diffusion MRI. Magn. Reson. Med. 2017, 77 (1), 285–299. https://doi.org/10.1002/mrm.26124. [doi]
3. Aghaeifar, A.; Bosch, D.; Heule, R.; Williams, S.; Ehses, P.; Mauconduit, F.; Scheffler, K. Intra‐scan RF Power Amplifier Drift Correction. Magn. Reson. Med. 2024, 92 (2), 645–659. https://doi.org/10.1002/mrm.30078. [doi]
4. Ward, K. M.; Aletras, A. H.; Balaban, R. S. A New Class of Contrast Agents for MRI Based on Proton Chemical Exchange Dependent Saturation Transfer (CEST). J. Magn. Reson. 2000, 143 (1), 79–87. https://doi.org/10.1006/jmre.1999.1956. [doi]
5. Wu, B.; Warnock, G.; Zaiss, M.; Lin, C.; Chen, M.; Zhou, Z.; Mu, L.; Nanz, D.; Tuura, R.; Delso, G. An Overview of CEST MRI for Non-MR Physicists. EJNMMI Phys. 2016, 3 (1), 19. https://doi.org/10.1186/s40658-016-0155-2. [doi]
6. Zhou, J.; Zaiss, M.; Knutsson, L.; Sun, P. Z.; Ahn, S. S.; Aime, S.; Bachert, P.; Blakeley, J. O.; Cai, K.; Chappell, M. A.; Chen, M.; Gochberg, D. F.; Goerke, S.; Heo, H.; Jiang, S.; Jin, T.; Kim, S.; Laterra, J.; Paech, D.; Pagel, M. D.; Park, J. E.; Reddy, R.; Sakata, A.; Sartoretti‐Schefer, S.; Sherry, A. D.; Smith, S. A.; Stanisz, G. J.; Sundgren, P. C.; Togao, O.; Vandsburger, M.; Wen, Z.; Wu, Y.; Zhang, Y.; Zhu, W.; Zu, Z.; Van Zijl, P. C. M. Review and Consensus Recommendations on Clinical APT ‐weighted Imaging Approaches at 3T : Application to Brain Tumors. Magn. Reson. Med. 2022, 88 (2), 546–574. https://doi.org/10.1002/mrm.29241. [doi]
7. Liebert, A.; Zaiss, M.; Gumbrecht, R.; Tkotz, K.; Linz, P.; Schmitt, B.; Laun, F. B.; Doerfler, A.; Uder, M.; Nagel, A. M. Multiple Interleaved Mode Saturation (MIMOSA) for B1+ Inhomogeneity Mitigation in Chemical Exchange Saturation Transfer. Magn. Reson. Med. 2019, 82 (2), 693–705. https://doi.org/10.1002/mrm.27762. [doi]
8. Zaiss, M.; Ehses, P.; Scheffler, K. Snapshot‐CEST: Optimizing Spiral‐centric‐reordered Gradient Echo Acquisition for Fast and Robust 3D CEST MRI at 9.4 T. NMR Biomed. 2018, 31 (4), e3879. https://doi.org/10.1002/nbm.3879. [doi]

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http://echo.ismrm.org/p/ISMRM2026/660-03-002