Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
451-02-003 / 451-02-003 ISMRM Abstract

Tissue sodium concentration and sodium T1 mapping of the monkey brain at 11.7 T using a Variable Flip Angle method

Primary: Contrast Mechanisms - Non-Proton
Secondary: Preclinical Animal & in vitro MR - Large Animals, Nonhuman Primates
451-02-003 · Advances in Contrast Mechanisms · Tuesday, 12 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
451-02-003 · Advances in Contrast Mechanisms · Tuesday, 12 May, 1:40 PM–3:16 PM · Power Pitch Theatre 1
Keywords: T1 Mapping Variable Flip Angles B0 correction 23-Sodium Total sodium concentration
Accepted
Mariam El Balq 1, Alfredo L Lopez Kolkovsky1, Maxime Roustan1, Thomas Lilin1, Marion Gay1, Armin M NAGEL2,3, Franck Mauconduit1, Fawzi Boumezbeur1
1CEA NeuroSpin, Paris-Saclay University, CNRS, Gif-Sur-Yvette, France
2Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
3Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
Presenting Author: Mariam El Balq

Synopsis

Motivation:
Goals:
Approach:
Results:
Full abstract & presentation

The full text, figures, and any recorded presentation for this abstract are not shown here. Log in if you are a member or registered attendee with access.

Full abstracts, figures, and presentations for Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition are available to registered attendees. This content becomes freely available to the public roughly two years after the meeting.

To request or purchase access, contact the ISMRM Central Office at info@ismrm.org.

Log in

References

1. Boada FE, LaVerde G, Jungreis C, Nemoto E, Tanase C, Hancu I. Loss of cell ion homeostasis and cell viability in the brain: what sodium MRI can tell us. Curr Top Dev Biol. 2005;70:77-101. doi: 10.1016/S0070-2153(05)70004-1. PMID: 16338338. [doi] [pmid]
2. Zaaraoui W, Konstandin S, Audoin B, Nagel AM, Rico A, Malikova I, Soulier E, Viout P, Confort-Gouny S, Cozzone PJ, Pelletier J, Schad LR, Ranjeva JP. Distribution of brain sodium accumulation correlates with disability in multiple sclerosis: a cross-sectional 23Na MR imaging study. Radiology. 2012 Sep;264(3):859-67. doi: 10.1148/radiol.12112680. Epub 2012 Jul 17. PMID: 22807483. [doi] [pmid]
3. Ladd ME, Bachert P, Meyerspeer M, Moser E, Nagel AM, Norris DG, Schmitter S, Speck O, Straub S, Zaiss M. Pros and cons of ultra-high-field MRI/MRS for human application. Prog Nucl Magn Reson Spectrosc. 2018 Dec;109:1-50. doi: 10.1016/j.pnmrs.2018.06.001. Epub 2018 Jun 8. PMID: 30527132. [doi] [pmid]
4. Coste A, Boumezbeur F, Vignaud A, Madelin G, Reetz K, Le Bihan D, Rabrait-Lerman C, Romanzetti S. Tissue sodium concentration and sodium T1 mapping of the human brain at 3 T using a Variable Flip Angle method. Magn Reson Imaging. 2019 May;58:116-124. doi: 10.1016/j.mri.2019.01.015. [doi]
5. Boulant N, Quettier L; Iseult Consortium. Commissioning of the Iseult CEA 11.7 T whole-body MRI: current status, gradient-magnet interaction tests and first imaging experience. MAGMA. 2023 Apr;36(2):175-189. doi: 10.1007/s10334-023-01063-5. Epub 2023 Jan 30. PMID: 36715884; PMCID: PMC10140097. [doi] [pmid]
6. Nagel AM, Laun FB, Weber MA, Matthies C, Semmler W, Schad LR. Sodium MRI using a density-adapted 3D radial acquisition technique. Magn Reson Med. 2009 Dec;62(6):1565-73. doi: 10.1002/mrm.22157. PMID: 19859915. [doi] [pmid]
7. Stollberger, R., Wach, P., McKinnon, G., Justich, E., & Ebner, F. (1988). RF-field mapping in vivo. In Proceedings of the Society of Magnetic Resonance in Medicine 1988 (pp. 106-106)
8. S.M. Smith. Fast robust automated brain extraction. Human Brain Mapping, 17(3):143-155, November 2002
9. Zhang, Y, Brady, M. and Smith, S. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans Med Imag, 20(1):45-57, 2001
10. Madelin G, Regatte RR. Biomedical applications of sodium MRI in vivo. J Magn Reson Imaging. 2013 Sep;38(3):511-29. doi: 10.1002/jmri.24168. Epub 2013 May 30. PMID: 23722972; PMCID: PMC3759542. [doi] [pmid]
11. Gast LV, Platt T, Nagel AM and Gerhalter T. Recent technical developments and clinical research applications of sodium (23Na) MRI, doi.org/10.1016/j.pnmrs.2023.04.002. [doi]

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/451-02-003