Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
552-01-007 / 552-01-007 ISMRM Abstract

Anterior Cingulate Creatine and Glutamate-GABA Balance in Relation to Anxiety and Obsessive and Compulsive Tendencies

Primary: Neuro - Neurotransmission
Secondary: Brain Function and fMRI - fMRI & Neuromodulation
552-01-007 · Novel Approaches to Spectroscopy · Wednesday, 13 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2
552-01-007 · Novel Approaches to Spectroscopy · Wednesday, 13 May, 8:20 AM–9:56 AM · Power Pitch Theatre 2
Keywords: Anxiety Magnetic Resonance Spectroscopy Obsessive and Compulsive Tendencies Anterior cingulate cortex
Accepted
Wei Su 1,2, Qianwen Zhang1,2, Xuan Li1,2, LingYang Zeng1,2, Zhengqi Zhu1,2, Jiaxiang xin3, Kaihua Zhang1,2
1Faculty of Psychology, Shandong Normal University, Jinan, China
2Shandong Provincial Key Laboratory of Brain Science and Mental Health, China
3MR Research Collaboration, Siemens Healthineers Ltd., Shanghai, China
Presenting Author: Wei Su

Synopsis

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References

1. Strom, N. I. et al. Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population. Mol. Psychiatry 29, 2714-2723 (2024).
2. Journée, S. H., Mathis, V. P., Fillinger, C., Veinante, P. & Yalcin, I. Janus effect of the anterior cingulate cortex: Pain and emotion. Neurosci. Biobehav. Rev. 153, 105362 (2023).
3. Brindle, K. M. Imaging cancer metabolism using magnetic resonance. Npj Imaging 2, 1 (2024).
4. Kosová, E. et al. Spectroscopic abnormalities in the pregenual anterior cingulate cortex in obsessive-compulsive disorder using proton magnetic resonance spectroscopy: a controlled study. BMC Psychiatry 23, 734 (2023).
5. Nakahara, T. et al. Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of 1H-magnetic resonance spectroscopy studies. Mol. Psychiatry 27, 744-757 (2022).
6. Hayes, A. F. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. (The Guilford Press, New York, 2013).

Cite this abstract

http://echo.ismrm.org/p/ISMRM2026/552-01-007