Cape Town - 2026 ISMRM-ISMRT Annual Meeting and Exhibition
9 May 2026 – 14 May 2026 · Cape Town, South Africa
468-03-002 ISMRM Abstract

Phasor based segmentation of porcine hearts in hyperpolarized 13C MRI

Primary: Analysis Methods - Segmentation and Detection
Secondary: Cardiovascular - Myocardium
468-03-002 · Segmentation for Cardiac Applications · Tuesday, 12 May, 1:40 PM–2:35 PM · Digital Posters Row I
Keywords: Segmentation Hyperpolarized 13C MRI Metabolic imaging Hyperpolarized 13C metabolic MRI Cardiovascular magnetic resonance imaging
Accepted
Konstantin Müller1,2, Christoffer Laustsen3, Esben S Hansen3, Josef Mayer2, Saar Székely2, Pascal P.R. Ruetten2
1Ulm University, Ulm, Germany
2NVision Imaging Technologies GmbH, Ulm, Germany
3The MR Research Centre, Aarhus University, Aarhus, Denmark
Presenting Author: Vencel Somai

Synopsis

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References

1. Vaeggemose M, Schulte RF, Laustsen C. Comprehensive literature review of hyperpolarized carbon-13 MRI: the road to clinical application. Metabolites. 2021;11(4):219. doi: 10.3390/metabo11040219. PMID: 33916803; PMCID: PMC8067176. [doi] [pmid]
2. Hsieh CY, Lai YC, Lu KY, Lin G. Advancements, challenges, and future prospects in clinical hyperpolarized magnetic resonance imaging: A comprehensive review. Biomed J. 2025 Jun;48(3):100802. doi: 10.1016/j.bj.2024.100802. PMID: 39442802; PMCID: PMC12181021. [doi] [pmid]
3. Bianchetti G, Ciccarone F, Ciriolo MR, De Spirito M, Pani G, Maulucci G. Label-free metabolic clustering through unsupervised pixel classification of multiparametric fluorescent images. Anal Chim Acta. 2021 Mar 1;1148:238173. doi: 10.1016/j.aca.2020.12.048. Epub 2020 Dec 31. PMID: 33516373. [doi] [pmid]
4. Bianchetti G, Spirito M, Maulucci G. Unsupervised clustering of multiparametric fluorescent images extends the spectrum of detectable cell membrane phases with sub-micrometric resolution. Biomed Opt Express. 2020 Sep 21;11(10):5728-5744. doi: 10.1364/BOE.399655. PMID: 33149982; PMCID: PMC7587257. [doi] [pmid]
5. Vallmitjana A, Torrado B, Gratton E. Phasor-based image segmentation: machine learning clustering techniques. Biomed Opt Express. 2021 May 17;12(6):3410-3422. doi: 10.1364/BOE.422766. PMID: 34221668; PMCID: PMC8221971. [doi] [pmid]
6. James Bankson, Peder E.Z. Larson, 6 - Analysis and visualization of hyperpolarized 13C MR data, Editor(s): Peder E.Z. Larson, Advances in Magnetic Resonance Technology and Applications, Academic Press, Volume 3, 2021, Pages 129-155, ISSN 2666-9099, ISBN 9780128222690, https://doi.org/10.1016/B978-0-12-822269-0.00004-X. [doi]
7. Matthew L. Zierhut, Yi-Fen Yen, Albert P. Chen, Robert Bok, Mark J. Albers, Vickie Zhang, Jim Tropp, Ilwoo Park, Daniel B. Vigneron, John Kurhanewicz, Ralph E. Hurd, Sarah J. Nelson, Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice, Journal of Magnetic Resonance, Volume 202, Issue 1, 2010, Pages 85-92, ISSN 1090-7807, https://doi.org/10.1016/j.jmr.2009.10.003. [doi]

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http://echo.ismrm.org/p/ISMRM2026/468-03-002